Use of 5α-reductase inhibitor and delay in prostate cancer diagnosis and treatment
Int. braz. j. urol; 46 (3), 2020
Results: 7
High D-dimer levels are associated with prostate cancer
Rev. Assoc. Med. Bras. (1992, Impr.); 66 (5), 2020
RESUMO OBJETIVO O câncer de próstata é uma das neoplasias mais comuns em homens. Os principais fatores de risco para a ativação da coagulação e trombose são malignidade e idade mais avançada. O risco de trombose pode estar associado ao aumento do nível dos marcadores de coagulação, tais com...
Discovery of the ARP2 protein as a determining molecule in tumor cell death
Gac. méd. Méx; 155 (5), 2019
Cancer is a multifactorial disease that constitutes a serious public health problem worldwide. Prostate cancer advanced stages are associated with the development of androgen-independent tumors and an apoptosis-resistant phenotype that progresses to metastasis. By studying androgen-independent lymphoid n...
Apoptosis/fisiología, Proteínas Reguladoras de la Apoptosis/aislamiento & purificación, Proteínas Reguladoras de la Apoptosis/metabolismo, Células CHO, Calcio/metabolismo, Canales de Calcio/metabolismo, Cricetulus, ADN Complementario/aislamiento & purificación, Óvulo/metabolismo, Neoplasias de la Próstata/metabolismo, Neoplasias de la Próstata/patología, ARN Mensajero/metabolismo, Xenopus laevis
Can expressed prostatic secretions affect prostate biopsy decision of urologist?
Int. braz. j. urol; 45 (2), 2019
ABSTRACT Objectives: To evaluate the frequency of NIH category IV prostatitis, and the use of expressed prostatic secretions tests in an effort to improve the reliability of prostate specific antigen as an indicator, to avoid unnecessary prostate biopsy. Materials and Methods: 178 expressed prostatic s...
Biomarcadores de Tumor/metabolismo, Biopsia/normas, Enfermedad Crónica, Diagnóstico Diferencial, Tacto Rectal, Persona de Mediana Edad, Estudios Prospectivos, Próstata/metabolismo, Próstata/patología, Antígeno Prostático Específico/sangre, Hiperplasia Prostática/diagnóstico, Hiperplasia Prostática/metabolismo, Neoplasias de la Próstata/diagnóstico, Neoplasias de la Próstata/metabolismo, Prostatitis/clasificación, Prostatitis/mortalidad, Prostatitis/patología
Prevalence of ERG expression and PTEN loss in a Brazilian prostate cancer cohort
Braz. j. med. biol. res; 52 (12), 2019
PTEN is the most commonly inactivated tumor suppressor gene in primary prostate cancer (PCa) and its loss is associated with poor clinical outcomes. ERG rearrangement is a genomic alteration frequently found in PCa and its prognostic significance has yielded mixed results. Although the association of PTE...
Biomarcadores de Tumor/sangre, Biomarcadores de Tumor/genética, Biomarcadores de Tumor/metabolismo, Estudios de Cohortes, Regulación Neoplásica de la Expresión Génica, Inmunohistoquímica, Clasificación del Tumor, Fosfohidrolasa PTEN/sangre, Fosfohidrolasa PTEN/genética, Fosfohidrolasa PTEN/metabolismo, Prevalencia, Pronóstico, Neoplasias de la Próstata/metabolismo, Neoplasias de la Próstata/patología, Neoplasias de la Próstata/cirugía, Estudios Retrospectivos, Regulador Transcripcional ERG/sangre, Regulador Transcripcional ERG/genética, Regulador Transcripcional ERG/metabolismo
The change in serum Thiol/Disulphide homeostasis after transrectal ultrasound guided prostate biopsy
Int. braz. j. urol; 43 (3), 2017
ABSTRACT Objectives The aim of this prospective clinical study was to investigate variations in a novel oxidative stress marker (thiol/disulphide homeostasis) in men who underwent transrectal ultrasound guided prostate biopsy (TRUSB). Materials and Methods A total of 22 men undergoing TRUSB of the pr...
Biomarcadores, Biopsia, Tacto Rectal, Disulfuros/metabolismo, Biopsia por Aspiración con Aguja Fina Guiada por Ultrasonido Endoscópico, Biopsia Guiada por Imagen, Estrés Oxidativo, Estudios Prospectivos, Próstata/patología, Antígeno Prostático Específico/metabolismo, Neoplasias de la Próstata/diagnóstico por imagen, Neoplasias de la Próstata/metabolismo, Compuestos de Sulfhidrilo/metabolismo, Ultrasonografía
Metabolic syndrome and prostatic disease: potentially role of polyphenols in preventive strategies. A review
Int. braz. j. urol; 42 (3), 2016
ABSTRACT Benign prostatic hyperplasia and prostate cancer are two common urological diseases of the elderly. Scientific community has always looked for a link that could explain the correlation between the two diseases and the role of chronic inflammation in the pathogenesis of BPH and PCa. As shown by t...
Antioxidantes/uso terapéutico, Síndrome Metabólico/tratamiento farmacológico, Síndrome Metabólico/prevención & control, Estrés Oxidativo/efectos de los fármacos, Polifenoles/uso terapéutico, Hiperplasia Prostática/tratamiento farmacológico, Hiperplasia Prostática/metabolismo, Hiperplasia Prostática/prevención & control, Neoplasias de la Próstata/tratamiento farmacológico, Neoplasias de la Próstata/metabolismo, Neoplasias de la Próstata/prevención & control, Resultado del Tratamiento