Beneficial effects of octreotide in alcohol-induced neuropathic pain. Role of H 2S, BDNF, TNF-α and Nrf2
Acta cir. bras; 36 (4), 2021
ABSTRACT Purpose To explore the role and molecular mechanisms of neuroprotective effects of octreotide in alcohol-induced neuropathic pain. Methods Male Wistar rats were employed and were administered a chronic ethanol diet containing 5% v/v alcohol for 28 days. The development of neuropathic pain was ...
Analgésicos/farmacología, Factor Neurotrófico Derivado del Encéfalo, Cistationina betasintasa, Etanol, Sulfuro de Hidrógeno, Hiperalgesia, Factor 2 Relacionado con NF-E2, Neuralgia/inducido químicamente, Neuralgia/tratamiento farmacológico, Octreótido/farmacología, Ratas Wistar, Factor de Necrosis Tumoral alfa, Cistationina gamma-Liasa