La córnea es el tejido más densamente inervado de nuestro organismo, debido a ello, las patologías que la afectan generan habitualmente dolor intenso. La cirugía refractiva
induce una noxa sobre ésta, la que puede inducir dolor de cuantía importante. En este artículo de revisión, se analizan las ...
INTRODUCTION: Lidocaine is a local anesthetic agent, with intravenous route indications for use in contexts different from symptom control in oncologic patients. Evidence regarding its usefulness in neuropathic pain and refractory pruritus exists. This review aims to describe available evidence supportin...
Abstract:
The aim of this study was to evaluate the functional interaction of
Glycyrrhiza glabra
root
extract (GGRE) on the large conductance Ca
2+
-
activated K
+
(BKCa) channels expressed in the peripheral
nervo
us system by using nociception and inflammation models in rodents
in vivo
....
Glycyrrhiza/química,
Neuralgia/tratamiento farmacológico,
Extractos Vegetales/administración & dosificación,
Nocicepción/efectos de los fármacos,
Subunidades alfa de los Canales de Potasio de Gran Conductancia Activados por Calcio/efectos de los fármacos,
Ratas Wistar,
Extractos Vegetales/farmacología,
Extractos Vegetales/química,
Fenoles/análisis,
Análisis de Varianza,
Raíces de Plantas,
Inflamación,
Modelos Animales
ABSTRACT Purpose To explore the role and molecular mechanisms of neuroprotective effects of octreotide in alcohol-induced neuropathic pain. Methods Male Wistar rats were employed and were administered a chronic ethanol diet containing 5% v/v alcohol for 28 days. The development of neuropathic pain was ...
Analgésicos/farmacología,
Factor Neurotrófico Derivado del Encéfalo,
Cistationina betasintasa,
Etanol,
Sulfuro de Hidrógeno,
Hiperalgesia,
Factor 2 Relacionado con NF-E2,
Neuralgia/inducido químicamente,
Neuralgia/tratamiento farmacológico,
Octreótido/farmacología,
Ratas Wistar,
Factor de Necrosis Tumoral alfa,
Cistationina gamma-Liasa
Reactive oxygen species (ROS) are involved in neuropathic pain, a complicated condition after nerve tissue lesion. Vitamin D appears to improve symptoms of pain and exhibits antioxidant properties. We investigated the effects of oral administration of vitamin D3, the active form of vitamin D, on nocicept...
Antioxidantes,
Peróxido de Hidrógeno,
Hiperalgesia/tratamiento farmacológico,
Neuralgia/tratamiento farmacológico,
Nocicepción,
Ratas Wistar,
Especies Reactivas de Oxígeno,
Nervio Ciático,
Médula Espinal,
Vitamina D,
Vitaminas
ABSTRACT Background: Central neuropathic pain (CNP) is often refractory to available therapeutic strategies and there are few evidence-based treatment options. Many patients with neuropathic pain are not diagnosed or treated properly. Thus, consensus-based recommendations, adapted to the available drugs...
The neurochemical mechanisms underlying neuropathic pain (NP) are related to peripheral and central sensitization caused by the release of inflammatory mediators in the peripheral damaged tissue and ectopic discharges from the injured nerve, leading to a hyperexcitable state of spinal dorsal horn neurons...
Resumen Muchos pacientes presentan dolores de cabeza primarios que no son tomados en cuenta en la consulta diaria de odontología. Es común que los asocien a un dolor referido a la articulación témporomandibular, inclusive a un dolor dental de origen no odontogénico, donde se ve incluida esta estruct...
Abstract Background and objectives: Calcitonin is a polypeptide hormone regulating the metabolism of calcium in the body. For many years calcitonin has been used to maintain and improve bone mineral density and to reduce the fracture rate. Many studies showed that calcitonin had analgesic role in severa...
Dolor Agudo/tratamiento farmacológico,
Dolor Agudo/etiología,
Dolor Agudo/fisiopatología,
Analgésicos/farmacología,
Analgésicos/uso terapéutico,
Calcitonina/farmacología,
Calcitonina/uso terapéutico,
Dolor Crónico/tratamiento farmacológico,
Dolor Crónico/etiología,
Dolor Crónico/fisiopatología,
Neuralgia/tratamiento farmacológico,
Neuralgia/etiología,
Neuralgia/fisiopatología
ABSTRACT Neuropathic pain is a chronic syndrome that is difficult to treat and often affects patients with leprosy. Recommended treatment includes the the use of analgesic drugs, codeine, tricyclic antidepressants, neuroleptics, anticonvulsants and thalidomide, but without consensus on uniform dose and f...
Analgésicos/uso terapéutico,
Toxinas Botulínicas Tipo A/uso terapéutico,
Dolor Crónico/tratamiento farmacológico,
Lepra/tratamiento farmacológico,
Lepra/fisiopatología,
Neuralgia/tratamiento farmacológico,
Fármacos Neuromusculares/uso terapéutico,
Dimensión del Dolor,
Calidad de Vida,
Reproducibilidad de los Resultados,
Encuestas y Cuestionarios,
Factores de Tiempo,
Resultado del Tratamiento
