Introducción. La esclerosis lateral amiotrófica (ELA) es una enfermedad degenerativa del sistema nervioso en la cual las neuronas motoras se desgastan y mueren, lo que se manifiesta con la aparición de debilidad muscular progresiva, espasmos e incapacidad para mover los brazos, las piernas y, finalmen...
Realizar uma revisão bibliográfica sobre os medicamentos específicos empregados no tratamento da Atrofia Muscular Espinhal (AME),
uma doença genética neurodegenerativa caracterizada por fraqueza nos membros e atrofia muscular. Revisão narrativa de literatura, realizada por meio de um estudo descrit...
Purpose:
Various postoperative protocols have been proposed to improve outcomes and accelerate nerve regeneration. Recently, the use of physical exercise in a post-surgical neurorraphy procedure has shown good results when started early. We experimentally investigated the hypothesis that post-operative e...
Fasciculations and cramps originate in the motor unit, a functional unit that includes the lower motor neuron and their innervated muscle fibres. Both are common complaints in outpatient practice. These symptoms can be secondary to neurological or medical pathology, presenting a broad differential diagno...
Esclerosis Amiotrófica Lateral/complicaciones,
Esclerosis Amiotrófica Lateral/diagnóstico,
Esclerosis Amiotrófica Lateral/terapia,
Electromiografía/efectos adversos,
Fasciculación/diagnóstico,
Fasciculación/etiología,
Fasciculación/terapia,
Neuronas Motoras/fisiología,
Calambre Muscular/diagnóstico,
Calambre Muscular/etiología,
Calambre Muscular/terapia
ANTECEDENTES: la evidencia sobre personas que presentan daño de motoneurona superior y desarrollan un patrón de espasticidad en extremidad superior (EES) es limitada. Este signo positivo de disfunción o secundario al daño de la motoneurona superior se asocia con pérdida de función y disminución de...
BACKGROUND Behavioral and neurochemical alterations associated with toxoplasmosis may be influenced by the persistence of tissue cysts and activation of an immune response in the brain of Toxoplasma gondii-infected hosts. The cerebral extracellular matrix is organised as perineuronal nets (PNNs) that ar...
Cerebelo/citología,
Cerebelo/metabolismo,
Modelos Animales de Enfermedad,
Matriz Extracelular/metabolismo,
Neuronas Motoras/citología,
Neuronas Motoras/metabolismo,
Neuronas/metabolismo,
Neuronas/patología,
Toxoplasma,
Toxoplasmosis/metabolismo,
Toxoplasmosis/patología,
Toxoplasmosis Animal
Recovery of motor function after central nervous system (CNS) injury is dependent on the regeneration capacity of the nervous system, which is a multifactorial process influenced, among other things, by the role of neuromodulators such as serotonin. The neurotransmitter serotonin can promote neuronal reg...
Abstract The aim of this study was to propose a mechanical device that could increase the mechanical load during the entire eccentric (ECC) action on a knee flexor machine and to compare the muscular activity when the device was used during a testing protocol. Fifteen physically active women were recruit...
ABSTRACT Motor neuron disease is one of the major groups of neurodegenerative diseases, mainly represented by amyotrophic lateral sclerosis. Despite wide genetic and biochemical data regarding its pathophysiological mechanisms, motor neuron disease develops under a complex network of mechanisms not restr...
ABSTRACT PURPOSE: To evaluate a new model of intraoperative electromyographic (EMG) assessment of the tibial and fibular nerves, and its respectives motor units in rats. METHODS: Eight Wistar rats underwent intraoperative EMG on both hind limbs at two different moments: week 0 and week 12. Supramaxima...
