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Toxoplasma gondii infection damages the perineuronal nets in a murine model

Meurer, Ywlliane da Silva Rodrigues; Brito, Ramayana Morais de Medeiros; da Silva, Valeria Palheta; Andade, Joelma Maria de Araujo; Linhares, Sarah Sophia Guedes; Pereira Junior, Antonio; de Andrade-Neto, Valter Ferreira; de Sá, Andrea Lima; Oliveira, Claudio Bruno Silva de.
Mem. Inst. Oswaldo Cruz; 115 (), 2020
BACKGROUND Behavioral and neurochemical alterations associated with toxoplasmosis may be influenced by the persistence of tissue cysts and activation of an immune response in the brain of Toxoplasma gondii-infected hosts. The cerebral extracellular matrix is organised as perineuronal nets (PNNs) that ar...
Cerebelo/citología, Cerebelo/metabolismo, Modelos Animales de Enfermedad, Matriz Extracelular/metabolismo, Neuronas Motoras/citología, Neuronas Motoras/metabolismo, Neuronas/metabolismo, Neuronas/patología, Toxoplasma, Toxoplasmosis/metabolismo, Toxoplasmosis/patología, Toxoplasmosis Animal
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