LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Oxidative stress on ischemia/reperfusion injury in mice with non-alcoholic hepatic steatosis or steatohepatitis

Cayuela, Natalie Chaves; Negreti, Gabrielly Pascoa; Rasslan, Roberto; Koike, Marcia Kiyomi; Montero, Edna Frasson de Souza.

Acta cir. bras; 33 (9), 2018

Abstract Purpose: To evaluate the oxidative stress, resulting from ischemia and hepatic reperfusion, in mice with non-alcoholic hepatic steatosis and steatohepatitis. Methods: C57BL/6 male mice were used. Part of them were ob/ob mice, and the other part was fed with standard or MCD diets - this last ...

Modelos Animales de Enfermedad, Peroxidación de Lípido/fisiología, Ratones Endogámicos C57BL, Nitritos/metabolismo, Enfermedad del Hígado Graso no Alcohólico/metabolismo, Enfermedad del Hígado Graso no Alcohólico/patología, Estrés Oxidativo/fisiología, Daño por Reperfusión/metabolismo, Daño por Reperfusión/patología

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Maternal administration of cannabidiol promotes an anti-inflammatory effect on the intestinal wall in a gastroschisis rat model

Callejas, GH; Figueira, RL; Gonçalves, FLL; Volpe, FAP; Zuardi, AW; Crippa, JA; Hallak, JE; Sbragia, L.

Braz. j. med. biol. res; 51 (5), 2018

Gastroschisis (GS) is an abdominal wall defect that results in histological and morphological changes leading to intestinal motility perturbation and impaired absorption of nutrients. Due to its anti-inflammatory, antioxidant, and neuroprotective effects, cannabidiol (CBD) has been used as a therapeutic ...

Antiinflamatorios/uso terapéutico, Cannabidiol/uso terapéutico, Modelos Animales de Enfermedad, Enteritis/prevención & control, Enfermedades Fetales/metabolismo, Enfermedades Fetales/patología, Gastrosquisis/metabolismo, Gastrosquisis/patología, Inmunohistoquímica, Intestinos/efectos de los fármacos, Nitratos/metabolismo, Óxido Nítrico Sintasa de Tipo II/análisis, Nitritos/metabolismo, Ratas Sprague-Dawley

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Aerobic Swim Training Restores Aortic Endothelial Function by Decreasing Superoxide Levels in Spontaneously Hypertensive Rats

Jordão, Camila P; Fernandes, Tiago; Tanaka, Leonardo Yuji; Bechara, Luiz R. Grassmann; de Sousa, Luis Gustavo Oliveira; Oliveira, Edilamar M; Ramires, Paulo Rizzo.

Clinics; 72 (5), 2017

OBJECTIVE: We aimed to determine whether aerobic training decreases superoxide levels, increases nitric oxide levels, and improves endothelium-dependent vasodilation in the aortas of spontaneously hypertensive rats. METHODS: Spontaneously hypertensive rats (SHR) and Wistar Kyoto rats (WKY) were distribu...

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