Identification of a type I nitroreductase gene in non-virulent Trypanosoma rangeli
Mem. Inst. Oswaldo Cruz; 112 (7), 2017
ABSTRACT Trypanosomatid type I nitroreductases (NTRs), i.e., mitochondrial enzymes that metabolise nitroaromatic pro-drugs, are essential for parasite growth, infection, and survival. Here, a type I NTR of non-virulent protozoan Trypanosoma rangeli is described and compared to those of other trypanosomat...