Results: 21

Posicionamiento conceptual para la identificación de fenotipos de obesidad al inicio de la gestación
Conceptual positioning for the obesity phenotypes identification at the beginning of pregnancy

Rev. cuba. med. mil; 52 (4), 2023
Los fenotipos de obesidad se presentan en individuos con igual índice de masa corporal que tienen diferentes perfiles metabólicos y pronósticos de salud. Su presencia desde etapas tempranas de la vida hace que incremente la probabilidad de que una mujer arribe al embarazo con estas características, p...

Efeitos da ingestão do suco de laranja Pera e suco de laranja Moro na microbiota intestinal e marcadores inflamatórios em indivíduos com obesidade

A obesidade é uma doença complexa que está associada inflamação crônica de baixo grau que contribui para o desenvolvimento de diversos distúrbios metabólicos como a resistência à insulina e estudos recentes sugerem a influência da microbiota intestinal no desenvolvimento e manutenção da doen...

Tyramine exerts hypolipidemic and anti-obesity effects in vivo

Abstract Obesity and dyslipidemia are conditions often associated with cardiovascular risk, inflammation, oxidative stress, and death. Thus, a new approach has been highlighted to promote research and development of pharmacological tools derived from natural sources. Among the most widely studied groups ...

Circulating IL-6, clusterin and irisin in obese subjects with different grades of obesity: association with insulin resistance and sexual dimorphism

ABSTRACT Objective: There are discrepancies about the relationship of IL-6, clusterin and irisin with obesity and obesity associated insulin resistance and also about their sexual dimorphism. This study aimed at evaluating the circulating levels of IL-6, clusterin and irisin in obese subjects of both se...

The effects of maternal obesity during gestation and lactation and orange juice intake on the metabolic profile of male offspring exposed to control and obesogenic diets and breast cancer risk of female offspring

Obesity is a worldwide public health problem and the main risk factor for a number of chronic diseases. Breast cancer is another worrisome disease: it is the leading cause of cancer amongst women and has an elevated mortality rate. Approximately 30 years ago, Barker and Trichopoulos suggested that cardio...

Caracterização de compostos bioativos de maracujá (Passiflora tenuifila) e efeito do seu consumo sobre marcadores bioquímicos, microbiota intestinal em indivíduos eutróficos e obesos

O maracujá (Passiflora ssp.) é conhecido por suas características sensoriais e por apresentar diversos compostos bioativos. Estudos prévios demonstraram que o consumo a longo prazo de maracujá melhorou os parâmetros bioquímicos, inflamatórios e antioxidantes. Uma espécie que tem despertado inter...

Conicity index in people with hypertension followed in the Brazil's Family Health Strategy

Rev. bras. enferm; 73 (5), 2020
ABSTRACT Objectives: to analyze the conicity index in people with hypertension followed in the Brazil's Family Health Strategy. Methods: cross-sectional study conducted in a medium-sized municipality located in the state of Paraná. Data collection took place in the first semester of 2016. using an ada...

Lupine as a potential agent against diet-induced obesity through adenosine monophosphate-activated protein kinase pathway: crude oil versus nanoemulsion formulations

Obesity represents a major challenge to the pharmaceutical community due to the minimal availability of anti-obesity drugs and the drawbacks of current weight-loss agents. The study described herein presents lupine oil, in two pharmaceutical formulations, as a potential anti-obesity agent via its effect ...

Efeito da administração dos sucos de laranja, cvs. Pera e Moro, sobre o estresse oxidativo e lipídios plasmáticos em indivíduos obesos com resistência à insulina

A obesidade é um dos principais fatores etiológicos do desenvolvimento da resistência à insulina, e ambos são responsáveis, em parte, pelo aumento do estresse oxidativo e diabete mellitus tipo 2. Vários estudos têm mostrado os benefícios de uma dieta rica em vegetais e frutas, devido à ação d...

Analysis of the transcriptional regulatory mechanisms mediated by microRNAs in Metabolic Syndrome

Metabolic Syndrome (MetS) is a combination of diseases interrelated and associated with increased mortality and risk of cardiovascular events. Among the elucidated molecular mechanisms of MetS, there are several genes regulated by miRNAs - small non-coding RNAs. A large number of transcriptomic studies i...