LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Beneficial effects of Cuscuta chinensis extract on glucocorticoid-induced osteoporosis through modulation of RANKL/OPG signals

Mo, Hui; Zhang, Ning; Li, Huifu; Li, Fan; Pu, Rong.

Braz. j. med. biol. res; 52 (12), 2019

Cuscuta chinensis Lam. (Convolvulaceae) is an important herbal medicine widely used to improve sexual function, treat osteoporosis, and prevent aging, and has been reported to exhibit anti-osteoporotic effects in vitro. However, the activity of Cuscuta chinensis Lam. on glucocorticoid-induced osteoporosi...

Western Blotting, Densidad Ósea/efectos de los fármacos, Cromatografía Líquida de Alta Presión, Cuscuta/química, Dexametasona/farmacología, Glucocorticoides/farmacología, Inmunohistoquímica, Osteoporosis/inducido químicamente, Osteoporosis/prevención & control, Osteoprotegerina/efectos de los fármacos, Osteoprotegerina/metabolismo, Extractos Vegetales/farmacología, Ligando RANK/efectos de los fármacos, Ligando RANK/metabolismo, ARN Mensajero, Ratas Sprague-Dawley

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Evolution of Periodontal Disease: Immune Response and RANK/RANKL/OPG System

Gibertoni, Fabrício; Sommer, Meire Ellen Ligia; Esquisatto, Marcelo Augusto Marretto; Amaral, Maria Esméria Corezola do; Oliveira, Camila Andrea de; Andrade, Thiago Antônio Moretti de; Mendonça, Fernanda Aparecida Sampaio; Santamaria-Jr, Milton; Felonato, Maíra.

Braz. dent. j; 28 (6), 2017

Abstract The aim of this study was to evaluate markers of bone loss and immune response present in evolution of periodontal disease. One hundred and two Wistar rats were divided into three animals groups: PD0, without ligation and PD15 days and PD60 days, submitted to ligation placement with a sterile 3-...

Western Blotting, Quimiocinas/metabolismo, Inmunohistoquímica, Inflamación/metabolismo, Osteoprotegerina/metabolismo, Enfermedades Periodontales/inmunología, Enfermedades Periodontales/metabolismo, Ligando RANK/metabolismo, Ratas Wistar, Receptor Activador del Factor Nuclear kappa-B/metabolismo, Reacción en Cadena de la Polimerasa de Transcriptasa Inversa

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The effects of chitosan oligosaccharides on OPG and RANKL expression in a rat osteoarthritis model

Zhang, Chun; Liao, Qi; Ming, Jiang-Hua; Hu, Ge-Liang; Chen, Qing; Liu, Shi-Qing; Li, Ya-Ming.

Acta cir. bras; 32 (6), 2017

Abstract Purpose: To investigate the effect of chitosan oligosaccharides (COS) against osteoarthritis (OA) and preliminarily discuss the osteoprotegerin (OPG), receptor activator of NF-κB ligand (RANKL) and RANK expression in a rat OA model. Methods: Thirty-six 6-week-old Male SD rats were randoml...

Cartílago Articular/efectos de los fármacos, Cartílago Articular/metabolismo, Quitosano/farmacología, Modelos Animales de Enfermedad, Regulación de la Expresión Génica, Oligosacáridos/farmacología, Osteoartritis/metabolismo, Osteoprotegerina/efectos de los fármacos, Osteoprotegerina/metabolismo, Ligando RANK/metabolismo, Ratas Sprague-Dawley

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Effects of IL-10 and glucose on expression of OPG and RANKL in human periodontal ligament fibroblasts

Zhang, L; Ding, Y; Rao, G Z; Miao, D.

Braz. j. med. biol. res; 49 (4), 2016

The effects of interleukin-10 (IL-10) and glucose on mRNA and protein expression of osteoprotegerin (OPG), and its ligand, receptor activator of nuclear factor-κB ligand (RANKL), were investigated in human periodontal ligament fibroblasts (HPDLFs). Primary HPDLFs were treated with different concentr...

Análisis de Varianza, Western Blotting, Células Cultivadas, Regulación hacia Abajo, Fibroblastos/efectos de los fármacos, Fibroblastos/metabolismo, Glucosa/farmacología, Interleucina-10/farmacología, Osteoprotegerina/metabolismo, Ligamento Periodontal/citología, Ligamento Periodontal/efectos de los fármacos, Ligando RANK/metabolismo, ARN Mensajero/análisis, Reacción en Cadena de la Polimerasa de Transcriptasa Inversa, Factores de Tiempo, Regulación hacia Arriba

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