LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Is the effect of melatonin on vascular endothelial growth factor receptor-2 associated with angiogenesis in the rat ovary?

Kandemir, Yasemin Behram; Konuk, Esma; Katırcı, Ertan; Xxx, Feride; Behram, Mustafa.

Clinics; 74 (), 2019

OBJECTIVES Vascular endothelial growth factor (VEGF) and its receptors play important roles in angiogenesis. Melatonin plays an important role in gonadal development; thus, its effect on the reproductive system is evident. We investigated the influence of melatonin on the expression of VEGF, vascular en...

Antioxidantes/metabolismo, Antioxidantes/farmacología, Catalasa/metabolismo, Peroxidación de Lípido, Malondialdehído/metabolismo, Melatonina/metabolismo, Melatonina/farmacología, Modelos Animales, Neovascularización Fisiológica/efectos de los fármacos, Ovario/irrigación sanguínea, Ovario/efectos de los fármacos, Ovario/enzimología, Ratas Wistar, Superóxido Dismutasa/metabolismo, Factor A de Crecimiento Endotelial Vascular/efectos de los fármacos, Receptor 2 de Factores de Crecimiento Endotelial Vascular/efectos de los fármacos

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The effects of an experimentally induced unilateral varicose ovarian vein on the activities of anti-oxidant enzymes in an adult rat ovary

In this study, we aim to examine effects of an experimentally induced unilateral varicose ovarian vein on the activities of anti-oxidant enzymes in an adult rat ovary. In this experimental study, a total of 30 adult female Wistar albino rats were divided into three groups. 10 rats in group 1 as the varic...