Results: 6

New and repurposed drugs to treat multidrug- and extensively drug-resistant tuberculosis

J. bras. pneumol; 44 (2), 2018
ABSTRACT Multidrug-resistant and extensively drug-resistant tuberculosis (MDR-TB and XDR-TB, respectively) continue to represent a challenge for clinicians and public health authorities. Unfortunately, although there have been encouraging reports of higher success rates, the overall rate of favorable out...

In vitro susceptibility of methicillin-resistant Staphylococcus aureus isolates from skin and soft tissue infections to vancomycin, daptomycin, linezolid and tedizolid

Braz. j. infect. dis; 21 (5), 2017
Abstract Introduction Treatment of multidrug-resistant Gram-positive infections caused by Staphylococcus aureus remains as a clinical challenge due to emergence of new resistance mechanisms. Tedizolid is a next-generation oxazolidinone, recently approved for skin and soft tissues infections. We conducte...

Avances en el tratamiento de la tuberculosis multirresistente

Resumen El tratamiento de las tuberculosis multidrogorresistentes (TBC-MDR) se basa en esquemas de fármacos con diseños muy variables, en pacientes con patrones de resistencia heterogéneos y seguimientos no estandarizados, lo que hace dificil plantear recomendaciones con fuerte nivel de evidencia. Ade...

Efficacy, safety, tolerability and population pharmacokinetics of tedizolid, a novel antibiotic, in Latino patients with acute bacterial skin and skin structure infections

Braz. j. infect. dis; 20 (2), 2016
Abstract Acute bacterial skin and skin structure infections are caused mainly by Gram-positive bacteria which are often treated with intravenous vancomycin, daptomycin, or linezolid, with potential step down to oral linezolid for outpatients. Tedizolid phosphate 200 mg once daily treatment for six days d...

Asociación de dicloxacilina y hetacilina en pediatría. Valoración clínica, bacteriológica y de tolerancia hemática, hepática y renal en 80 niños
[Combination of dicloxacillin and hetacillin in pediatrics. Clinical and bacteriological evaluation, and blood, hepatic and renal tolerance in 80 children]

Arch. argent. pediatr; 69 (9), 1971