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Tres interrogantes de interés en pancreatitis aguda y crónica

Armas Pérez, Bárbaro Agustín.
Rev. medica electron; 41 (2), 2019
Pancreatitis Aguda Necrotizante/etiología, Pancreatitis Aguda Necrotizante/diagnóstico, Pancreatitis Aguda Necrotizante/patología, Pancreatitis Crónica/diagnóstico, Pancreatitis Crónica/etiología, Pancreatitis Crónica/patología, Alcoholismo/complicaciones, Cálculos Biliares/complicaciones, Cálculos Biliares/cirugía, Triglicéridos/análisis, Conductos Pancreáticos/fisiopatología, Fibrosis/diagnóstico, Hemorragia/diagnóstico, Necrosis
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Ameliorative effect of certolizumab on experimentally induced acute necrotic pancreatitis in rats

Kosekli, Mehmet Ali; Herek, Özkan; Ozmen, Özlem; Sahinduran, Sima.
Rev. Assoc. Med. Bras. (1992, Impr.); 65 (2), 2019
SUMMARY OBJECTIVE: The effects of Certolizumab, a pegylated monoclonal antibody to tumor necrosis factor α, on experimentally induced acute pancreatitis (AP) were examined. METHODS: Thirty-six Wistar Albino male rats were randomly divided into four groups. Group I was the control group and no medi...
Certolizumab Pegol/uso terapéutico, Modelos Animales de Enfermedad, Inmunosupresores/uso terapéutico, Pancreatitis Aguda Necrotizante/inducido químicamente, Pancreatitis Aguda Necrotizante/tratamiento farmacológico, Pancreatitis Aguda Necrotizante/patología, Ratas Wistar, Ácido Taurocólico
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Glycogen synthase kinase-3 beta inhibitors protectagainst the acute lung injuries resulting from acute necrotizing pancreatitis

Jin, Hongzhong; Yang, Xiaojia; Zhao, Kailiang; Zhao, Liang; Chen, Chen; Yu, Jia.
Acta cir. bras; 34 (6), 2019
Abstract Purpose The research is intended for clarification of the efficacy as well as the underlying mechanism of GSK-3β inhibitors on the advancement of acute lung injuries in acute necrotizing pancreatitis (ANP) in rats. Methods Seventy-two rats were randomly divided into 6 groups: (1)ANP-veh...
Lesión Pulmonar Aguda/etiología, Lesión Pulmonar Aguda/metabolismo, Lesión Pulmonar Aguda/patología, Lesión Pulmonar Aguda/prevención & control, Modelos Animales de Enfermedad, Glucógeno Sintasa Quinasa 3 beta/antagonistas & inhibidores, Inmunohistoquímica, Interleucina-1beta/metabolismo, FN-kappa B/metabolismo, Pancreatitis Aguda Necrotizante/complicaciones, Pancreatitis Aguda Necrotizante/patología, Fosforilación, Ratas Wistar, Transducción de Señal, Factor de Necrosis Tumoral alfa/metabolismo
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Effects of diazoxide in experimental acute necrotizing pancreatitis

de Oliveira Andrade, Roberta; Kunitake, Tiago; Koike, Marcia Kiyomi; Machado, Marcel C C; Souza, Heraldo Possolo.
Clinics; 72 (2), 2017
OBJECTIVE: We aimed to assess the effects of diazoxide on the mortality, pancreatic injury, and inflammatory response in an experimental model of acute pancreatitis. METHODS: Male Wistar rats (200-400 g) were divided randomly into two groups. Fifteen minutes before surgery, animals received physiologica...
Colagogos y Coleréticos, Diazóxido/administración & dosificación, Diazóxido/farmacología, Modelos Animales de Enfermedad, Pancreatitis Aguda Necrotizante/inducido químicamente, Pancreatitis Aguda Necrotizante/tratamiento farmacológico, Pancreatitis Aguda Necrotizante/mortalidad, Pancreatitis Aguda Necrotizante/patología, Distribución Aleatoria, Ratas Wistar, Ácido Taurocólico, Vasodilatadores/administración & dosificación, Vasodilatadores/farmacología
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