Results: 2

Gene expression of Paracoccidioides virulence factors after interaction with macrophages and fibroblasts

Mem. Inst. Oswaldo Cruz; 116 (), 2021
BACKGROUND Paracoccidioidomycosis (PCM) is a systemic mycosis with high prevalence in Latin America that is caused by thermodimorphic fungal species of the Paracoccidioides genus. OBJECTIVES In this study, we used quantitative polymerase chain reaction (qPCR) to investigate the expression of genes rel...

Epidemiology of paracoccidioidomycosis in Venezuela: a retrospective study from 1954 to 2019

Mem. Inst. Oswaldo Cruz; 116 (), 2021
BACKGROUND Paracoccidioidomycosis (PCM) is a systemic mycosis endemic to Latin America. Etiological agents are Paracoccidioides species that diverge phylogenetically throughout South America. OBJECTIVES This study aimed to document the epidemiology of PCM in Venezuela. METHODS We have performed a re...