LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Hypericum perforatum chronic treatment affects cognitive parameters and brain neurotrophic factor levels

Valvassori, Samira S; Borges, Cenita; Bavaresco, Daniela V; Varela, Roger B; Resende, Wilson R; Peterle, Bruna R; Arent, Camila; Budni, Josiane; Quevedo, João.

Braz. J. Psychiatry (São Paulo, 1999, Impr.); 40 (4), 2018

Objective: To evaluate the effects of Hypericum perforatum (hypericum) on cognitive behavior and neurotrophic factor levels in the brain of male and female rats. Methods: Male and female Wistar rats were treated with hypericum or water during 28 days by gavage. The animals were then subjected to the ope...

Cognición/efectos de los fármacos, Relación Dosis-Respuesta a Droga, Lóbulo Frontal/efectos de los fármacos, Lóbulo Frontal/metabolismo, Hipocampo/efectos de los fármacos, Hipocampo/metabolismo, Hypericum, Locomoción/efectos de los fármacos, Memoria/efectos de los fármacos, Modelos Animales, Factores de Crecimiento Nervioso/análisis, Factores de Crecimiento Nervioso/efectos de los fármacos, Patrones de Reconocimiento Fisiológico/efectos de los fármacos, Extractos Vegetales/administración & dosificación, Extractos Vegetales/farmacología, Distribución Aleatoria, Ratas Wistar, Factores Sexuales, Resultado del Tratamiento

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Facial emotional recognition in schizophrenia: preliminary results of the virtual reality program for facial emotional recognition

BACKGROUND: Significant deficits in emotional recognition and social perception characterize patients with schizophrenia and have direct negative impact both in inter-personal relationships and in social functioning. Virtual reality, as a methodological resource, might have a high potential for assessmen...