LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

The OxyR and SoxR transcriptional regulators are involved in a broad oxidative stress response in Paraburkholderia xenovorans LB400

Méndez, Valentina; Rodríguez-Castro, Laura; Durán, Roberto E; Padrón, Gabriel; Seeger, Michael.

Biol. Res; 55 (), 2022

BACKGROUND: Aerobic metabolism generates reactive oxygen species that may cause critical harm to the cell. The aim of this study is the characterization of the stress responses in the model aromatic degrading bacterium Paraburkholderia xenovorans LB400 to the oxidizing agents paraquat and H 2 O2. METHODS...

Proteínas de Escherichia coli/genética, Proteínas de Escherichia coli/metabolismo, Proteínas Bacterianas/genética, Proteínas Bacterianas/metabolismo, Escherichia coli/genética, Regulación Bacteriana de la Expresión Génica, Peróxido de Hidrógeno/farmacología, Proteínas Represoras/genética, Proteínas Represoras/metabolismo, Espectrometría de Masas en Tándem, Estrés Oxidativo, Oxidación-Reducción, Cromatografía Liquida, Burkholderiaceae

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Genetic regulation of the ompX porin of Salmonella Typhimurium in response to hydrogen peroxide stress

Briones, A. C; Lorca, D; Cofre, A; Cabezas, C. E; Krüger, G. I; Pardo-Esté, C; Baquedano, M. S; Salinas, C. R; Espinoza, M; Castro-Severyn, J; Remonsellez, F; Hidalgo, A. A; Morales, E. H; Saavedra, C. P.

Biol. Res; 55 (), 2022

BACKGROUND: Salmonella Typhimurium is a Gram negative pathogen that causes a systemic disease in mice resembling typhoid fever. During its infective cycle, S. Typhimurium is phagocytized by macrophages and proliferates inside a Salmonella containing vacuole where Salmonella is exposed and survives oxidat...

Proteínas de la Membrana Bacteriana Externa/genética, Porinas/genética, Porinas/metabolismo, Salmonella typhimurium/genética, Salmonella typhimurium/metabolismo, Regulación Bacteriana de la Expresión Génica, Peróxido de Hidrógeno/metabolismo, Peróxido de Hidrógeno/farmacología, ARN Bacteriano/genética, ARN Bacteriano/metabolismo

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A novel gene from the acidophilic bacterium Leptospirillum sp. CF-1 and its role in oxidative stress and chromate tolerance

Rivera Araya, Javier; Riveros, Matías; Ferrer, Alonso; Chávez, Renato; Levicán, Gloria.

Biol. Res; 55 (), 2022

BACKGROUND: Acidophilic microorganisms like Leptospirillum sp. CF 1 thrive in environments with extremely low pH and high concentrations of dissolved heavy metals that can induce the generation of reactive oxygen species (ROS). Several hypothetical genes and proteins from Leptospirillum sp. CF 1 are know...

Cromatos/metabolismo, Peróxido de Hidrógeno/metabolismo, Peróxido de Hidrógeno/farmacología, Bacterias/genética, Proteínas Bacterianas/genética, Proteínas Bacterianas/metabolismo, Estrés Oxidativo/genética, Especies Reactivas de Oxígeno/metabolismo, Operón, Escherichia coli

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Actin filaments mediated root growth inhibition by changing their distribution under UV-B and hydrogen peroxide exposure in Arabidopsis

Du, Meiting; Wang, Yanhong; Chen, Huize; Han, Rong.

Biol. Res; 53 (), 2020

BACKGROUND: UV-B signaling in plants is mediated by UVR8, which interacts with transcriptional factors to induce root morphogenesis. However, research on the downstream molecules of UVR8 signaling in roots is still scarce. As a wide range of functional cytoskeletons, how actin filaments respond to UV-B-i...

Citoesqueleto de Actina/fisiología, Arabidopsis/crecimiento & desarrollo, Peróxido de Hidrógeno/farmacología, Raíces de Plantas/crecimiento & desarrollo, Rayos Ultravioleta, Arabidopsis/efectos de la radiación, Proteínas de Arabidopsis, Proteínas Cromosómicas no Histona

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Gastrodin induced HO-1 and Nrf2 up-regulation to alleviate H2O2-induced oxidative stress in mouse liver sinusoidal endothelial cells through p38 MAPK phosphorylation

Zhang, Hongbin; Yuan, Bo; Huang, Hanfei; Qu, Siming; Yang, Shikun; Zeng, Zhong.

Braz. j. med. biol. res; 51 (10), 2018

Nuclear factor erythroid-related factor 2 (Nrf2) has been implicated in several detoxifying and antioxidant defense processes. Nrf2-mediated heme oxygenase-1 (HO-1) expression was demonstrated to play a key role against oxidative stress. Gastrodin (GSTD) is a well-known active compound isolated from the ...

Apoptosis/efectos de los fármacos, Alcoholes Bencílicos/farmacología, Supervivencia Celular/efectos de los fármacos, Células Endoteliales/efectos de los fármacos, Glucósidos/farmacología, Hemo-Oxigenasa 1/metabolismo, Peróxido de Hidrógeno/farmacología, Hígado/citología, Hígado/efectos de los fármacos, Malondialdehído/metabolismo, Modelos Teóricos, Regulación hacia Arriba/efectos de los fármacos, Proteínas Quinasas p38 Activadas por Mitógenos/metabolismo

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Melatonin ameliorates H2O2-induced oxidative stress through modulation of Erk/Akt/NFkB pathway

Moniruzzaman, Mahammed; Ghosal, Indranath; Das, Debjit; Chakraborty, Suman Bhusan.

Biol. Res; 51 (), 2018

BACKGROUND: Improper control on reactive oxygen species (ROS) elimination process and formation of free radicals causes tissue dysfunction. Pineal hormone melatonin is considered a potent regulator of such oxidative damage in different vertebrates. Aim of the current communication is to evaluate the leve...

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Arctiin blocks hydrogen peroxide-induced senescence and cell death though microRNA expression changes in human dermal papilla cells

Bae, Seunghee; Lim, Kyung Mi; Cha, Hwa Jun; An, In-Sook; Lee, Jeong Pyo; Lee, Kwang Sik; Lee, Ghang Tai; Lee, Kun Kook; Jung, Ho Jung; Ahn, Kyu Joong; An, Sungkwan.

Biol. Res; 47 (), 2014

BACKGROUND: Accumulating evidence indicates that reactive oxygen species (ROS) are an important etiological factor for the induction of dermal papilla cell senescence and hair loss, which is also known alopecia. Arctiin is an active lignin isolated from Arctium lappa and has anti-inflammation, anti-micro...

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