Rehman, S U;
Muhammad, K;
Novaes, E;
Que, Y;
Din, A;
Islam, M;
Porto, A C M;
Sajid, M;
Ullah, N;
Iqsa, S.
Abstract Transcription factors (TF) are a wide class of genes in plants, and these can regulate the expression of other genes in response to various environmental stresses (biotic and abiotic). In the current study, transcription factor activity in sugarcane was examined during cold stress. Initially, RN...
Purpose: This study evaluated the DNA damage caused by repeated doses of xylazine-ketamine and medetomidine-ketamine anesthesia in the liver and kidneys. Methods: In this study, 60 rats were used. The rats were divided into group 1 (xylazine-ketamine), and group 2 (medetomidine-ketamine), and these anes...
Introdução: Exposições químicas podem variar em populações geograficamente distintas, com diferentes hábitos, estilos de vida e características individuais. Alguns elementos químicos encontrados no ambiente são capazes de alterar a expressão gênica humana. Objetivos: a) quantificar as concen...
BACKGROUND: Drought stress has significantly hampered agricultural productivity worldwide and can also result in modifications to DNA methylation levels. However, the dynamics of DNA methylation and its association with the changes in gene transcription and alternative splicing (AS) under drought stress ...
INTRODUÇÃO: O câncer de bexiga é a 10a neoplasia maligna mais comum no mundo. O tipo músculo-invasivo tem como tratamento padrão-ouro combinações de quimioterapia e cirurgia. Muitos pacientes, no entanto, não respondem a quimioterapia e são submetidos a uma terapia ineficaz. Identificar quais p...
O carcinoma renal de células claras (CRCC) é o tipo de neoplasia renal com maior incidência, cerca de 80%. A maioria dos casos são curados após cirurgia, porém, cerca de um terço dos pacientes apresentam recidiva da doença com metástase à distância. O tratamento para este tumor evoluiu muito n...
Background Triatoma infestans is the main vector of Chagas disease in the Southern Cone. The resistance to pyrethroid insecticides developed by populations of this species impairs the effectiveness of vector control campaigns in wide regions of Argentina. The study of the global transcriptomic response t...
Background
Although domestic infestations by Triatoma infestans have been successfully controlled across Latin America, in areas of the Gran Chaco region, recurrent post-spraying house colonization continues to be a significant challenge, jeopardizing Chagas disease vector control and maintaining active ...
Tumor heterogeneity is the concept that different tumor cells provide distinct
biomorphological lesions, gene expressions, proliferation, microenvironment and
graduated capacity of metastatic lesions. Brain tumor heterogeneity has been recently
discussed about the interesting interaction of chronic infla...
Neoplasias Encefálicas/genética,
Heterogeneidad Genética,
Evolución Clonal/genética,
Células Madre Neoplásicas/citología,
Glioma/genética,
Nicho de Células Madre/genética,
Microambiente Tumoral,
Microambiente Celular/genética,
Proteínas Tirosina Quinasas Receptoras/genética,
Resistencia a Antineoplásicos/genética,
Perfilación de la Expresión Génica,
RNA-Seq
ABSTRACT Objective: Interstitial cystitis (IC)/bladder pain syndrome (BPS) is a chronic inflammatory disease that can cause bladder pain and accompanying symptoms, such as long-term urinary frequency and urgency. IC/BPS can be ulcerative or non-ulcerative. The aim of this study was to explore the core g...