Pericyte loss and detachment in experimental cisplatin-induced neuropathy
Int. j. morphol; 37 (2), 2019
Cisplatin is an antineoplastic agent with neuropathy as one of its major side effect. However, effective treatment is lacking. Increasing evidence suggests that cisplatin might damage nerve capillaries leading to impaired functions of blood-nerve barrier (BNB) and neuropathy. This study was aimed to exam...
Enfermedades del Sistema Nervioso/inducido químicamente, Enfermedades del Sistema Nervioso/patología, Pericitos/efectos de los fármacos, Cisplatino/toxicidad, Antineoplásicos/toxicidad, Pericitos/patología, Inmunohistoquímica, Microscopía Electrónica de Transmisión, Ratas Wistar, Peso Corporal/efectos de los fármacos