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Association between Periodontitis, Genetic Polymorphisms and Presence of Coronary Artery Disease in Southern Brazil

Rocha, Luiz Otavio; Rocha, Eduarda; Succi, Guilherme de Menezes; Brito Junior, Rui Barbosa de.
Arq. bras. cardiol; 114 (2), 2020
Abstract Background: Periodontitis and coronary artery disease (CAD) share an inflammatory etiology; there is a recent concern regarding the investigation of an association between these two conditions. Current theories indicate that cytokines and proteins have an important role in this process. C-react...
Factores de Edad, Alelos, Brasil, Proteína C-Reactiva/análisis, Proteína C-Reactiva/genética, Enfermedad de la Arteria Coronaria/complicaciones, Enfermedad de la Arteria Coronaria/genética, Interleucina-6/análisis, Interleucina-6/genética, Modelos Logísticos, Periodontitis/complicaciones, Periodontitis/genética, Reacción en Cadena de la Polimerasa, Polimorfismo de Nucleótido Simple, Factores de Riesgo, Factores Sexuales
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Upregulation of IL-10 expression inhibits the proliferation of human periodontal ligament stem cells

Liu, Yu; Yang, Jie; Sun, Weibin.
Braz. oral res. (Online); 34 (), 2020
Abstract: The abnormal increase in proliferation rate of human periodontal ligament stem cells (PDLSCs) is considered to be involved in the pathogenesis of periodontitis, a disease in which the IL-10-mediated anti-inflammatory pathway plays a critical role. This study aimed to investigate the involvement...
Western Blotting, Diferenciación Celular, Proliferación Celular/fisiología, Interleucina-10/metabolismo, Interleucina-10/uso terapéutico, MicroARNs/metabolismo, Periodontitis/genética, Periodontitis/metabolismo, Periodontitis/terapia, Células Madre/metabolismo, Regulación hacia Arriba
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miR-9-1 gene methylation and DNMT3B (rs2424913) polymorphism may contribute to periodontitis

Coêlho, Marina Castro; Queiroz, Ingrid Costa; Viana Filho, José Maria Chagas; Aquino, Sabrina Garcia de; Persuhn, Darlene Camati; Oliveira, Naila Francis Paulo de.
J. appl. oral sci; 28 (), 2020
Abstract Genetic and epigenetic changes have been associated with periodontitis in various genes; however, little is known about genes involved in epigenetic mechanisms and in oxidative stress. Objective: This study aims to investigate the association of polymorphisms C677T in MTHFR (rs1801133) and W...
Estudios de Casos y Controles, Catalasa/genética, ADN (Citosina-5-)-Metiltransferasas/genética, Metilación de ADN/genética, Estudios de Asociación Genética, Genotipo, Metilenotetrahidrofolato Reductasa (NADPH2)/genética, MicroARNs/genética, Periodontitis/genética, Reacción en Cadena de la Polimerasa, Polimorfismo Genético, Polimorfismo de Longitud del Fragmento de Restricción, Superóxido Dismutasa-1/genética
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