Fernandez, Carla María Mariano;
Kleinubing, Sirlene Adriana;
Karam, Thaysa Ksiaskiewcz;
Lorenzetti, Fabiana Brusco;
Palomo, Carolina Trevisolli;
Moreira de Oliveira, Byanca Pereira;
Goncalves, Odinei Hess;
Gazim, Zilda Cristiani;
Romagnolo, Mariza Barion;
Caleffi Ferracioli, Katiany Rizzieri;
Scodro, Regiane Bertin de Lima;
Lima, Marli Miriam de Souza;
Nakamura, Tania Ueda;
Nakamura, Celso Vataru;
Dias Filho, Benedito Prado.
The present study thus aimed at the development and physicochemical characterization of solid
lipid nanoparticles loaded with crude extract of
Piper corcovadensis
roots (SLN
-
CEPc) and chitosan
-
coated solid lipid nanoparticles loaded with
crude extract of
P. corcovadensis
roots (...
Piper/química,
Extractos Vegetales/administración & dosificación,
Lípidos,
Mycobacterium tuberculosis/efectos de los fármacos,
Sistemas de Liberación de Medicamentos,
Antibacterianos/administración & dosificación,
Portadores de Fármacos,
Cromatografía Líquida de Alta Presión,
Quitosano,
Temperatura,
Nanopartículas,
Raíces de Plantas
The aim of this study was to identify the chemical composition of the Piper arboreum Aubl. essential oil (EO), and to evaluate its inhibitory activity in vitro against the enzymes butyrylcholinesterase (BuChE) and acetylcholinesterase (AChE). The EO was obtained by steam distillation of t...
Piper kadsura (Choisy) Ohwi which belongs to the family Piperaceae, is a well-known medicinal plant possessing high medicinal and various therapeutic properties. It is widely used in traditional Chinese medicine for the treatment of asthma and rheumatic arthritis. Numerous studies on this species have al...
Piper/química,
Antiinflamatorios/química,
Antiinflamatorios/farmacología,
Lignanos/análisis,
Alcaloides/análisis,
Plantas Medicinales,
Aceites Volátiles/química,
Fitoquímicos/análisis,
Piperaceae/química,
Medicina Tradicional China,
Kadsura
Chemical constituents and biological activities of the aerial parts of Piper erecticaule C.DC. have been studied for the first time. Fractionation and purification of the extracts afforded aristolactam AII (1), aristolactam BII (2), piperolactam A (3), piperolactam C (4), piperolactam D (5), together wit...
Piper/química,
Extractos Vegetales/química,
Alcaloides/farmacología,
Alcaloides/química,
Aporfinas/farmacología,
Aporfinas/química,
Lactamas/química,
Alcaloides Indólicos/química,
Terpenos/aislamiento & purificación,
Acetilcolinesterasa/efectos de los fármacos,
Inhibidores de la Colinesterasa/farmacología,
Inhibidores de la Colinesterasa/química
Oliveira, Flávio Augusto de Souza;
Passarini, Guilherme Matos;
Medeiros, Daniel Sol Sol de;
Santos, Ana Paula de Azevedo;
Fialho, Saara Neri;
Gouveia, Aurileya de Jesus;
Latorre, Marcinete;
Freitag, Elci Marlei;
Medeiros, Patrícia Soares de Maria de;
Teles, Carolina Bioni Garcia;
Facundo, Valdir Alves.
Abstract INTRODUCTION This study assessed the activity of compounds from Piper tuberculatum against Plasmodium falciparum and Leishmania guyanensis. METHODS The effects of compounds from P. tuberculatum fruits on P. falciparum and L. guyanensis promastigote growth in vitro were determined. Hemolytic ...
Abstract Piper tuberculatum (Piperaceae) is a species that accumulates especially amides as secondary metabolites and several biological activities was previously reported. In this article, we report a proteomic study of P. tuberculatum. Bidimensional electrophoresis (2D SDS-PAGE) and mass spectrometry (...
Electroforesis en Gel Bidimensional,
Piper/química,
Piper/metabolismo,
Piper/fisiología,
Proteínas de Plantas/análisis,
Proteínas de Plantas/química,
Proteínas de Plantas/fisiología,
Proteoma/análisis,
Proteoma/química,
Proteoma/fisiología,
Proteómica,
Espectrometría de Masa por Ionización de Electrospray
ABSTRACT Piper aduncum found naturally in the Amazon and southeastern Brazil, is known for its secondary metabolites that have activity on insects. Anticarsia gemmatalis and Spodoptera frugiperda are among the major insect pests associated with agricultural production. This research evaluated the biologi...
Abstract The anthelminthic activity of the essential oil (EO) of Piper aduncum L. was tested in vitro on eggs and larvae of resistant (Embrapa2010) and susceptible (McMaster) isolates of Haemonchus contortus. The EO was obtained by steam distillation and its components identified by chromatography. EO co...
RESUMEN Objetivos. Evaluar el efecto cicatrizante del extracto hidroetanólico de Piper aduncum, en una línea celular de fibroblastos Dermales Adultos Humanos (hDFa). Materiales y métodos. El extracto se obtuvo mediante extracción sólido-líquido, fue concentrado y liofilizado. Se purificaron las...
ResumenEntre los principales compuestos químicos sintetizados por las plantas, pero considerados no esenciales para su metabolismo básico, están los alcaloides, los polifenoles, los glucósidos cianogénicos y las saponinas que tienen diversas funciones en las plantas y reconocidas propiedades medicin...
Alcaloides/análisis,
Artemia/efectos de los fármacos,
Artemisia absinthium/química,
Asteraceae/química,
Asteraceae/toxicidad,
Bioensayo,
Ecuador,
Euphorbiaceae/química,
Glicósidos/análisis,
Piper/química,
Extractos Vegetales/química,
Plantas Medicinales/química,
Polifenoles/análisis,
Saponinas/análisis,
Metabolismo Secundario,
Factores de Tiempo,
Taraxacum/química
