Development of microparticles and microparticulated tablets containing piperine
Braz. J. Pharm. Sci. (Online); 59 (), 2023
Abstract Piper nigrum (black pepper) is used in Indian traditional medicine and its main alkaloid, Piperine (PIP), presents antioxidant, antitumor and neuroprotective pharmacological properties. This substance is insoluble in aqueous media and can irritate the gastrointestinal tract. Aiming to avoid thes...
Piper nigrum/efectos adversos, Composición de Medicamentos/instrumentación, d0002840, Alcaloides/efectos adversos, Antioxidantes/efectos adversos, Análisis Espectral/métodos, Comprimidos/clasificación, Medicina Tradicional/instrumentación, Microscopía Electrónica de Rastreo/métodos, Tracto Gastrointestinal/anomalías, Técnicas In Vitro/métodos