Vandetanib induced phototoxic reaction progressed to toxic epidermal necrolysis
An. bras. dermatol; 97 (1), 2022
Results: 3
Rare complications of multikinase inhibitor treatment
Arch. endocrinol. metab. (Online); 62 (6), 2018
ABSTRACT Objective: The advent of multikinase inhibitor (MKI) therapy has led to a radical change in the treatment of patients with advanced thyroid carcinoma. The aim of this manuscript is to communicate rare adverse events that occurred in less than 5% of patients in clinical trials in a subset of pat...
Antineoplásicos/efectos adversos, Carcinoma/tratamiento farmacológico, Carcinoma Medular/tratamiento farmacológico, Estudios de Seguimiento, Insuficiencia Cardíaca/inducido químicamente, Perforación Intestinal/inducido químicamente, Estimación de Kaplan-Meier, Ooforitis/inducido químicamente, Compuestos de Fenilurea/efectos adversos, Piperidinas/efectos adversos, Inhibidores de Proteínas Quinasas/efectos adversos, Quinazolinas/efectos adversos, Quinolinas/efectos adversos, Estudios Retrospectivos, Factores de Riesgo, Sorafenib/efectos adversos, Trombocitopenia/inducido químicamente, Neoplasias de la Tiroides/tratamiento farmacológico, Factores de Tiempo
Medullary thyroid carcinoma - Adverse events during systemic treatment: risk-benefit ratio
Arch. endocrinol. metab. (Online); 61 (4), 2017
ABSTRACT Medullary thyroid carcinoma (MTC) is a rare neuroendocrine tumor originating from parafollicular C cells of the thyroid and associated with mutations in the proto-oncogene REarranged during Transfection (RET). The prognosis of MTC depends on clinical stage, with a 95.6% 10-year survival rate amo...
Anilidas/efectos adversos, Anilidas/uso terapéutico, Carcinoma Neuroendocrino/tratamiento farmacológico, Carcinoma Neuroendocrino/metabolismo, Piperidinas/efectos adversos, Piperidinas/uso terapéutico, Inhibidores de Proteínas Quinasas/efectos adversos, Inhibidores de Proteínas Quinasas/uso terapéutico, Piridinas/efectos adversos, Piridinas/uso terapéutico, Quinazolinas/efectos adversos, Quinazolinas/uso terapéutico, Medición de Riesgo, Neoplasias de la Tiroides/tratamiento farmacológico, Neoplasias de la Tiroides/metabolismo