Objetivo: identificar a incidência, fatores de risco e desfechos associados ao infarto agudo do miocárdio sem obstrução de artérias coronárias (myocardial infarction with nonobstructive coronary arteries – MINOCA). Método: estudo de coorte prospectivo em prontuários clínicos num hospital terci...
Aim: To evaluate the prevalence of soft tissue calcifications in orofacial region and their panoramic radiographic characteristics using digital panoramic radiographs among patients reporting to a tertiary dental hospital. Methods: 1,578 digital panoramic radiographs were retrieved from the archives and ...
La tomografía de coherencia óptica (OCT) es una técnica de imagen endovascular con elevada resolución espacial que permite evaluar las diferentes estructuras que componen la pared de las arterias coronarias, caracterizar morfológicamente la placa aterosclerótica y establecer el mecanismo fisiopatol...
Tomografía de Coherencia Óptica,
Infarto del Miocardio/diagnóstico por imagen,
Trombosis Coronaria/diagnóstico por imagen,
Cineangiografía,
Infarto del Miocardio/fisiopatología,
Infarto del Miocardio/terapia,
Infarto del Miocardio/tratamiento farmacológico,
Trombosis Coronaria/tratamiento farmacológico,
Estenosis Coronaria/diagnóstico por imagen,
Estenosis Coronaria/tratamiento farmacológico,
Placa Aterosclerótica/diagnóstico por imagen,
Placa Aterosclerótica/tratamiento farmacológico
Pipek, Leonardo Zumerkorn;
Rabelo, Nícollas Nunes;
Pipek, Henrique Zumerkorn;
Telles, Joao Paulo Mota;
Barbat, Natalia Camargo;
Coelho, Antônio Carlos Samaia da Silva;
Yoshikawa, Marcia Harumy;
Barbosa, Guilherme Bitencourt;
Teixeira, Manoel Jacobsen;
Figueiredo, Eberval Gadelha.
Introduction Intracranial aneurysm (IA) is a major healthcare concern. The use of statin to reduce serum cholesterol has shown evidence to reduce cardiovascular risk in various diseases, but the impact on IA has not been described. This study aims to determine whether statin use, and serum cholesterol le...
Purpose:
To evaluate the risk factors for poor outcomes after surgical and endovascular treatment of aneurysmal subarachnoid hemorrhage (aSAH).
Methods:
Patients with ≥ 18-years of age and aSAH were included, while patients who died within 12 h of admission or lost follow-up were excluded. All partici...
Cardiovascular diseases (CVDs) are the main cause of mortality worldwide, being the ischemic heart disease responsible for 85% of deaths. Atherosclerosis is a chronic inflammation of the arteries that underlies ischemic forms of CVD and involves the innate and adaptive immune systems, from initial fatty ...
Ácidos Docosahexaenoicos/análisis,
Nanocápsulas/análisis,
Aterosclerosis/patología,
Placa Aterosclerótica/metabolismo,
Antiinflamatorios/administración & dosificación,
Arterias/anomalías,
Causalidad,
Enfermedades Cardiovasculares/clasificación,
Estrategias de Salud,
Molécula-1 de Adhesión Celular Endotelial de Plaqueta,
Nanopartículas,
Preparaciones Farmacéuticas/análisis
SUMMARY: Statins inhibit cholesterol synthesis, but also have other pleiotropic effects. There are indications that they affect macrophage survival trough the regulation of apoptosis. We analyzed 50 samples of aortic wall, selected based on statins in patients' therapy (n=25, Th-S group) or statin-free t...
Inhibidores de Hidroximetilglutaril-CoA Reductasas/administración & dosificación,
Aterosclerosis/metabolismo,
Apoptosis/efectos de los fármacos,
Proteína bcl-X/metabolismo,
Genes bcl-2/fisiología,
Macrófagos/efectos de los fármacos,
Aorta/efectos de los fármacos,
Aterosclerosis/tratamiento farmacológico,
Placa Aterosclerótica,
Factores de Riesgo,
Medición de Riesgo
Abstract Background Stroke and acute myocardial infarction (AMI) are cardiovascular diseases commonly characterized by the development of atheromatous plaques associated with major complications and high mortality rates. Objective To identify an epidemiological trend in hospitalizations due to stroke...
Placa Aterosclerótica,
Atención Primaria de Salud,
Accidente Cerebrovascular/epidemiología,
Infarto del Miocardio/epidemiología,
Hospitalización,
Programas Nacionales de Salud,
Factores de Tiempo,
Brasil/epidemiología,
Estudios Ecológicos,
Consorcios de Salud,
Accidente Cerebrovascular/prevención & control,
Infarto del Miocardio/prevención & control
Resumo Fundamento A aterosclerose, em alguns casos, é uma condição assintomática, sendo necessário conhecer o grau de comprometimento arterial provocado pelas placas e sua associação com os fatores de risco. O exame de autópsia permite a compreensão dos processos básicos de doenças, assim com...
