Molecular variation of Plasmodium vivax dehydrofolate reductase in Mexico and Nicaragua contrasts with that occurring in South America
Salud pública Méx; 62 (4), 2020
Abstract: Objective: To research mutations associated to pyrimethamine resistance in dihydrofolate reductase (pvdhfr) of Plasmodium vivax from Mexico and Nicaragua and compare it to that reported in the rest of America. Materials and methods: Genomic DNA was obtained from P. vivax-infected blood samp...
Variación Genética, Plasmodium vivax/genética, Tetrahidrofolato Deshidrogenasa/genética, Antiprotozoarios/farmacología, Brasil, Colombia, Guyana Francesa, Honduras, Resistencia a los Insecticidas/genética, México, Mutación, Nicaragua, Plasmodium vivax/enzimología, Pirimetamina/farmacología, América del Sur