Results: 2

Antifungal pharmacodynamics: Latin America's perspective

Gonzalez, Javier M; Rodriguez, Carlos A; Agudelo, Maria; Zuluaga, Andres F; Vesga, Omar.

Braz. j. infect. dis; 21 (1), 2017

Abstract The current increment of invasive fungal infections and the availability of new broad-spectrum antifungal agents has increased the use of these agents by non-expert practitioners, without an impact on mortality. To improve efficacy while minimizing prescription errors and to reduce the high mone...

Antifúngicos/farmacocinética, Antifúngicos/uso terapéutico, Área Bajo la Curva, Aspergilosis/tratamiento farmacológico, Aspergilosis/metabolismo, Azoles/farmacocinética, Azoles/uso terapéutico, Candidiasis/tratamiento farmacológico, Candidiasis/metabolismo, Relación Dosis-Respuesta a Droga, Equinocandinas/farmacocinética, Equinocandinas/uso terapéutico, América Latina, Pruebas de Sensibilidad Microbiana, Polienos/farmacocinética, Polienos/uso terapéutico, Triazoles/farmacocinética, Triazoles/uso terapéutico

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Extracellular phospholipase production of oral Candida albicans isolates from smokers, diabetics, asthmatics, denture wearers and healthy individuals following brief exposure to polyene, echinocandin and azole antimycotics

Ellepola, Arjuna N. B; Samaranayake, L. P; Khan, Z. U.

Braz. j. microbiol; 47 (4), 2016

Abstract Objective Candida albicans is the primary causative agent of oral candidosis, and one of its key virulent attributes is considered to be its ability to produce extracellular phospholipases that facilitate cellular invasion. Oral candidosis can be treated with polyenes, and azoles, and the more ...

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