LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Acteoside Attenuates Recognition Memory Impairment in CUMS Rats via Regulating Synaptic Plasticity and mTOR Signaling Pathway

Sun, Manli; Fan, Wenjuan; Wang, Xinghong; Meng, Jin; Zhang, Fuhua; Chang, Quanzhong; Deng, Haifeng.

Int. j. morphol; 42 (2), 2024

SUMMARY: We evaluated the role and mechanism of acteoside in the regulation of memory impairment induced by chronic unpredictable mild stress (CUMS). CUMS was used to induce depression in rats and the successful establishment of CUMS model were verified by forced swimming test and sucrose preference test...

Estrés Psicológico/complicaciones, Trastornos de la Memoria/tratamiento farmacológico, Glucósidos/administración & dosificación, Glucósidos/uso terapéutico, Polifenoles/administración & dosificación, Polifenoles/uso terapéutico, Reconocimiento en Psicología/efectos de los fármacos, Plasticidad Neuronal/efectos de los fármacos, Serina-Treonina Quinasas TOR/antagonistas & inhibidores, Depresión/tratamiento farmacológico, Modelos Animales de Enfermedad, Ratas Sprague-Dawley, Escala de Evaluación de la Conducta, Neuronas, Técnica del Anticuerpo Fluorescente, Western Blotting, Aprendizaje por Laberinto, Inhibidores mTOR

Fulltext

Polyphenols for improvement of inflammation and symptoms in rheumatic diseases: systematic review

Coletro, Hillary Nascimento; Diniz, Amanda Popolino; Guimarães, Nathália Sernizon; Carraro, Júlia Cristina Cardoso; Mendonça, Raquel de Deus; Meireles, Adriana Lúcia.

Säo Paulo med. j; 139 (6), 2021

ABSTRACT BACKGROUND: Rheumatic diseases (RDs) are a group of pathological conditions characterized by inflammation and functional disability. There is evidence suggesting that regular consumption of polyphenols has therapeutic effects capable of relieving RD symptoms. OBJECTIVE: To synthesize data from...

Inflamación, Metaanálisis como Asunto, Polifenoles/uso terapéutico, Enfermedades Reumáticas/tratamiento farmacológico, Revisiones Sistemáticas como Asunto

Fulltext

Antihypoxic activities of Crataegus pentaegyn and Crataegus microphylla fruits-an in vivo assay

Ebrahimzadeh, Mohammad Ali; Khalili, Masoumeh; Jafari, Negar; Zareh, Giti; Farzin, Davood; Amin, Gholamreza.

Braz. J. Pharm. Sci. (Online); 54 (2), 2018

ABSTRACT The aim of this study was to evaluate anti-hypoxia activity of polyphenolic extracts of Crataegus microphylla and Crataegus pentaegyn on mice. Three experimental models of hypoxia were considered, including asphyctic hypoxia, haemic hypoxia, and circulatory hypoxia. Polyphenolic extract of both ...

Crataegus/efectos adversos, Hipoxia/tratamiento farmacológico, Polifenoles/uso terapéutico, Cromatografía Líquida de Alta Presión/métodos, Frutas/clasificación, Extractos Vegetales/análisis

Fulltext

Metabolic syndrome and prostatic disease: potentially role of polyphenols in preventive strategies. A review

Castelli, Tommaso; Russo, Giorgio Ivan; Reale, Giulio; Privitera, Salvatore; Chisari, Mario; Fragalà, Eugenia; Favilla, Vincenzo; Cimino, Sebastiano; Morgia, Giuseppe.

Int. braz. j. urol; 42 (3), 2016

ABSTRACT Benign prostatic hyperplasia and prostate cancer are two common urological diseases of the elderly. Scientific community has always looked for a link that could explain the correlation between the two diseases and the role of chronic inflammation in the pathogenesis of BPH and PCa. As shown by t...

Antioxidantes/uso terapéutico, Síndrome Metabólico/tratamiento farmacológico, Síndrome Metabólico/prevención & control, Estrés Oxidativo/efectos de los fármacos, Polifenoles/uso terapéutico, Hiperplasia Prostática/tratamiento farmacológico, Hiperplasia Prostática/metabolismo, Hiperplasia Prostática/prevención & control, Neoplasias de la Próstata/tratamiento farmacológico, Neoplasias de la Próstata/metabolismo, Neoplasias de la Próstata/prevención & control, Resultado del Tratamiento

Fulltext