Results: 10

Modulación por Passiflora edulis de triglicéridos y colesterol intracelulares en líneas celulares de cáncer colorrectal SW480 y sus derivadas metastásicas (SW620)

Cancer cells modify lipid metabolism to proliferate, Passiflora edulis ( P. edulis ) fruit juice (ZuFru) has antitumor activity, but whether a mechanism is through modulation of cell lipids is unknown. T o establish if ZuFru modifies cholesterol and triglycerides in SW480 and SW620...

Locust bean gum hydrogels are bioadhesive and improve indole-3-carbinol cutaneous permeation: influence of the polysaccharide concentration

Abstract The locust bean gum (LBG) is a polysaccharide with thickening, stabilizing and gelling properties and it has been used in the preparation of pharmaceutical formulations. Hydrogels (HGs) are obtained from natural or synthetic materials that present interesting properties for skin application. Thi...

Quantification of anti-nutritional factors and their correlations with protein and oil in soybeans

An. acad. bras. ciênc; 90 (1), 2018
ABSTRACT Soybeans contain about 30% carbohydrate, mainly consisting of non-starch polysaccharides (NSP) and oligosaccharides. NSP are not hydrolyzed in the gastrointestinal tract of monogastric animals. These NSP negatively affect the development of these animals, especially the soluble fraction. This wo...

Efeito do processamento químico e térmico do farelo de trigo na solubilização de polissacarí­deos benéficos para a saúde humana

A ingestão regular de fibras alimentares pode auxiliar na redução do risco de certas doenças crônicas, como doenças cardiovasculares, síndromes metabólicas, diabetes tipo 2 e alguns tipos de câncer. Dentre as principais fontes de fibras alimentares, destaca-se o grão de trigo, que é rico em fi...

Polissacarídeo capsular do Streptococcus agalactiae como antígeno vacinal: desenvolvimento de um modelo vacinal para mucosas com Nanopartícula de quitosana

A bactéria gram-positiva Streptococcus agalactiae do grupo B (GBS) faz parte da microbiota normal do trato geniturinário humano, sendo um organismo comensal do corpo da mulher. No entanto, em mulheres grávidas, quando há alterações na composição microbiana do canal vaginal, pode ocorrer a prolife...

Sucrose induced dentin demineralization in a microcosm biofilm model

The aim of this in vitro study was to assess the root dentin demineralization caused by a microcosm biofilm model that has been exposed to sucrose in different ways. Materials and Methods: Saliva of two volunteers was inoculated into an artificial medium for biofilm growth and dentin blocks were immersed...

Formulation, in vitro drug release and in vivo human X-ray investigation of polysaccharide based drug delivery systems for targeting 5-fluorouracil to the colon

Braz. j. pharm. sci; 49 (2), 2013
The purpose of this research study was to develop 5-fluorouracil compression coated tablets by using biodegradable polysaccharide polymer locust bean gum (LBG) and hydroxyl propyl methyl cellulose (HPMC) as coating materials. The fast disintegrating core tablets containing 50 mg of 5-fluorouracil were co...

Immediate and long-term effects of polysaccharides-based formulations on human skin

Braz. j. pharm. sci; 48 (3), 2012
A new trend in cosmetic formulations is the use of biotechnological raw materials as the polysaccharides from Klebsiella pneumoniae, which are supposed to enhance cell renewal, improve skin hydration and micro-relief. Botanical extracts of Myrtus communis leaves contain different sugars, which may provid...

Aproveitamento do amido de alimentos estudos em humanos e animais

Foram realizados ensaios de curta e media duracao em animais e humanos visando avaliar o aproveitamento do amido do feijao em relacao a outras fontes de carboidratos complexos, de consumo habitual da populacao brasileira. Em animais, o aumento da glicose plasmatica decorrente da ingestao de diferentes fo...

Estudo histoquímico de glicans do tecido de granulaçäo de feridas cutâneas e citofotometria da glândula tireóide de ratos hipotireoideos, parotidectomizados e parotidectomizados hipotireoideos

O objetivo deste trabalho é o de realizar um estudo histoquímico de glicans no citoplasma de fibroblastos, fibrócitos, substância intercelular e zon de edema do tecido de granulaçäo de feridas cutâneas, assim como analisar citofotometricamente o DNA nuclear de células foliculares tireoideanas de ...