Protective effects of Polygonatum sibiricum polysaccharide on acute heart failure in rats
Acta cir. bras; 33 (10), 2018
Abstract Purpose: To investigate the protective effects of Polygonatum sibiricum polysaccharide (PSP) on acute heart failure (AHF) in rats. Methods: Sixty rats were randomly divided into control, model, and low-, middle- and high-dose PSP groups, 12 rats in each group. The low-, medium- and high-dose...
Enfermedad Aguda, Apoptosis/efectos de los fármacos, Modelos Animales de Enfermedad, Doxorrubicina/farmacología, Insuficiencia Cardíaca/prevención & control, Estrés Oxidativo/efectos de los fármacos, Polygonatum/química, Polisacáridos/uso terapéutico, Ratas Sprague-Dawley, Proteína X Asociada a bcl-2/efectos de los fármacos, Proteína X Asociada a bcl-2/metabolismo