Results: 41

Development, physicochemical evaluation, and in vivo permeation studies of topical formulations containing 0.1% tacrolimus

Abstract The objective of this paper was to develop and evaluate two semi-solid pharmaceutical forms containing 0.1% tacrolimus: cream (CRT01) and gel (GLT01). For the evaluation of physicochemical stability, at times 0, 30, 60 and 90 days, at 23°C and at 40°C, High Performance Liquid Chromatography co...

Effect of Cissus quadrangularis on Fracture Healing in Laboratory Animal

Objectives: The present study was designed to examine the efficacy of Cissus quadrangularis paste on fracture healing in artificially induced fractured rabbits. Methods: Fifteen rabbits were separated into three groups namely A, B, and C. Veldt grape paste was applied in groups B and C (Treatment Group)...

Walnut ointment promotes full-thickness burning wound healing: role of linoleic acid

Acta cir. bras; 37 (9), 2022
Purpose: To investigate the active ingredients of walnut ointment (WO) and its mechanism in repairing wounds. Methods: The ingredients of WO were detected by gas chromatography–mass spectrometry. The effect of linoleic acid (LA) was tested by in vitro Alamar Blue (AB) reagent. Image J software, histol...

Mupirocin ointments: In vitro x In vivo bioequivalence evaluation

Abstract Bioequivalence (BE) assessment of topical drug products is a long-standing challenge. Agencies such as the Food and Drug Administration (FDA) and the European Medicines Agency (EMA) have published several drafts in recent years suggesting different approaches as alternative to evaluate the BE. A...

Estudo ex vivo da elevação do pH em superfície radicular externa após agitação ultrassônica de diferentes pastas de hidróxido de cálcio

Dent. press endod; 11 (2), 2021
Objetivo: O presente estudo teve por objetivo avaliar, ex vivo, a capacidade de elevação do pH da superfície radicular externa de diferentes pastas de hidróxido de cálcio (HC) utilizadas como medicação intracanal, além da influência da ativação ultrassônica (AUS) durante aplicação no interi...

Application of chen yuangao in the treatment of soft tissue injury of football players

Rev. bras. med. esporte; 27 (spe2), 2021
ABSTRACT The treatment of soft tissue injury in football players generally includes physical therapy, anti-inflammatory and analgesic drug treatment, surgical treatment and early rest immobilization. Western medicine treatment of soft tissue injury can quickly heal the wound and relieve pain in a short t...

Efficacy and mechanism of traditional chinese medicine gel in sports-related soft tissue injury

Rev. bras. med. esporte; 27 (spe2), 2021
ABSTRACT Soft tissue injury is the most common disease in orthopedics, and it is also the most easily neglected disease in sports. Without timely and effective treatment, it is easy to develop into malignant strain and seriously affect life and sports. In view of this, the aim of this study is to analyze...

Wound healing effect of Pistacia lentiscus L. seed oil: confirmation of its uses in Mediterranean traditional medicine

In order to evaluate the potential of this formulation (P. lentiscus L. oil-based ointment) to heal wounds, experimental wounds were done on guinea pigs and efficiency was comparatively assessed against a reference ointment, Cicaderma®. Wound contraction was performed on days 5, 10 and 15. Tissue sectio...

Abordagem conservadora do ectrópio palpebral congênito

Rev. bras. oftalmol; 79 (2), 2020
Resumo Ectrópio palpebral congênito é o termo utilizado para descrever a ocorrência da eversão das pálpebras, seja ela superior ou inferior, presente ao nascimento. Trata-se de uma afecção rara com reduzido número de casos publicados no meio científico desde 1896, ano em que o primeiro relato f...

Caracterización físico-química de la pomada de Maytenus laevis “Chuchuhuasi” elaborada en la Farmacia Natural del Hospital III EsSalud Chimbote
Physicochemical characterization of Maytenus laevis "chuchuhuasi" ointment, elaborated at the Natural Pharmacy of Hospital III EsSalud, Chimbote

Rev. peru. med. integr; 5 (4), 2020
Objetivos. Determinar las características físicoquímicas de la pomada de Maytenus laevis «chuchuhuasi», elaborada en la Farmacia Natural del CAMEC del Hospital III EsSalud - Chimbote. Materiales y métodos. Investigación analítica-descriptiva. Se elaboró un extracto etanólico mediante maceració...