Results: 4

Preparation and characterisation of Dextran-70 hydrogel for controlled release of praziquantel

Braz. j. pharm. sci; 49 (1), 2013
A hydrogel was developed from 70 kDa dextran (DEX-70) and praziquantel (PZQ) incorporated as a model drug. Biopharmaceutical properties, such as solubility and dissolution rate, were analysed in the design of the hydrogel. Furthermore, the hydrogel was also characterized by IR spectroscopy and DSC. Tests...

Efecto in vitro de prazicuantel sobre la actividad de Giardia intestinalis
In vitro effects of praziquantel over the trophozoites of Giardia intestinalis

Rev. mex. pueric. ped; 6 (27), 1998
Se realizó un estudio in vitro para conocer el efecto farmacológico de prazicuantel sobre los trofozoítos de Giardia intestinalis cepa P-1. Después de cultivarlos axénicamente, con cinco diferentes concentraciones de prazicuantel (de 0.32 hasta 1.62 nM/mL) durante 24 h a 37ºC, la viabilidad y la CI...