MicroRNA-98 inhibits the cell proliferation of human hypertrophic scar fibroblasts via targeting Col1A1
Biol. Res; 50 (), 2017
BACKGROUND: Hypertrophic scarring (HS) is a severe disease, and results from unusual wound healing. Col1A1 could promote the hypertrophic scar formation, and the expression of Col1A1 in HS tissue was markedly higher than that in the normal. In present study, we aimed to identify miRNAs as post-transcript...
Apoptosis/genética, Colágeno Tipo I/metabolismo, Fibroblastos/metabolismo, MicroARNs/genética, Procesamiento Postranscripcional del ARN/genética, Cicatriz Hipertrófica/genética, Cicatriz Hipertrófica/metabolismo, Colágeno Tipo I/genética, MicroARNs/metabolismo, Estudios de Casos y Controles, Proliferación Celular, Regulación hacia Abajo