Results: 7

Pam2CSK4 (TLR2 agonist) induces periodontal destruction in mice

Abstract Lipoproteins are important bacterial immunostimulating molecules capable of inducing receptor activator of nuclear factor-κB (RANKL) and osteoclast formation in vitro and in vivo . Although these molecules are present in periodontopathogenic bacteria, their role in periodontitis is not know...

Pam2CSK4 (TLR2 agonist) induces periodontal destruction in mice

Abstract Lipoproteins are important bacterial immunostimulating molecules capable of inducing receptor activator of nuclear factor-κB (RANKL) and osteoclast formation in vitro and in vivo . Although these molecules are present in periodontopathogenic bacteria, their role in periodontitis is not know...

Losartan improves alveolar bone dynamics in normotensive rats but not in hypertensive rats

J. appl. oral sci; 27 (), 2019
Abstract Hypertension is one of the main causes of premature death in the world; also, it is associated with several bone alterations. Preclinical studies have demonstrated delayed alveolar bone healing in hypertensive rats. However, losartan has been favorable for consolidation of bone grafts and reduct...

Effect of acute administration of nicotine and ethanol on tooth movement in rats

Abstract The aim of this study was to evaluate the effect of acute administration of nicotine and ethanol on tooth movement in rats. Two hundred rats were divided into eight groups: S: saline; N: nicotine; E: ethanol; NE: nicotine and ethanol; SM: saline with tooth movement; NM: nicotine with tooth movem...

Fluoxetine effects on periodontogenesis: histomorphometrical and immunohistochemical analyses in rats

J. appl. oral sci; 25 (2), 2017
Abstract Reports have indicated that serotonin plays an important role in cell migration and differentiation during the organogenesis of several tissues, including the oral types. Administration of selective serotonin reuptake inhibitor (SSRI) drugs during pregnancy could affect the delivery of serotonin...

Bisfosfonato e movimentaçäo dentária induzida: avaliaçäo microscópica de seus efeitos

Os biofosfonatos säo eficientes bloqueadores das reabsorçöes e, por isso, säo utilizados no controle das doenças metabólicas ósseas. Os mecanismos pelos quais essas drogas interferem nos processos de reabsorçäo ainda näo estäo totalmente esclarecidos, mas incluem a inibiçäo da funçäo e a a...

Efeito do parotin sobre o processo de reparo em ferida de extraçäo dental: estudo morfológico em ratos

Foi propósito deste trabalho, analisar morfologicamente o processo de reparo em feridas de extraçäo dental em ratos injetados com Parotin. Nas condiçöes experimentais do presente trabalho, baseados nos resultados obtidos, foi possível concluir que a administraçäo do Parotin ocasionou: 1) aumento ...