Abstract Infusion solutions must be stable from the production stage until the infusion stage. Some infusion fluids contain degradation products, known as advanced glycation end products (AGEs); however, it is unknown whether AGEs exist in parenteral nutrition solutions. We aimed to investigate this ques...
Abstract TCMSP platform of systematic pharmacology of traditional Chinese medicine This study aimed to investigate the molecular mechanism of Fructus Ligustri Lucidi (NZZ, Chinese abbreviation) against osteoporosis (OP) by means of network pharmacology.ChemDraw Professional 15.1 software and Molinspirati...
Investigación/clasificación,
Ligustrum/efectos adversos,
Osteoporosis/patología,
Medicina Tradicional China,
Farmacología en Red/instrumentación,
Factor de Necrosis Tumoral alfa/farmacología,
Genes,
Interleucina-17/análogos & derivados,
Ontología de Genes,
Pueblos del Este de Asia,
Productos Finales de Glicación Avanzada/efectos adversos,
Programas Informáticos/clasificación
SUMMARY OBJECTIVE: To investigate the associations of high-mobility group box 1 and its specific receptor, receptor for advanced glycation end products with acute lung injury in patients with acute aortic dissection. METHODS: A total of 96 acute aortic dissection patients were divided into acute aortic...
Abstract Background: Patients with chronic kidney disease (CKD) are affected by dynapenia, sarcopenia, and vascular calcification. Advanced glycation end products (AGEs) may accumulate in peritoneal dialysis (PD) patients and favor sarcopenia via changes in collagen cross-linking, muscle protein breakdo...
O diabetes mellitus (DM) é um grande problema de saúde pública, que afeta cerca de 463 milhões de pessoas no mundo e pode alcançar 700 milhões de pessoas até 2045. A nefropatia é uma das complicações microvasculares do diabetes e a maior causa de insuficiência renal. Uma vez que a ativação d...
Abstract Objective: This study evaluated the effects of local vitamin C treatment on tissue advanced glycation end products (AGE), interleukin (IL)-6, 8-hydroxy-2-deoxyguanosine (8-OHdG), and matrix metalloproteinases (MMP)-8 in tissues; serum C-terminal telopeptide fragments (CTX); and alveolar bone lo...
Pérdida de Hueso Alveolar,
Ácido Ascórbico/administración & dosificación,
Colágeno Tipo I,
Diabetes Mellitus Experimental/complicaciones,
Diabetes Mellitus Experimental/tratamiento farmacológico,
Productos Finales de Glicación Avanzada,
Interleucina-6,
Metaloproteinasa 8 de la Matriz,
Estrés Oxidativo,
Péptidos,
Periodontitis/tratamiento farmacológico,
Ratas Sprague-Dawley
La cocción de los alimentos a altas temperaturas en calor seco, produce ciertas modificaciones organolépticas que los hace especialmente apetecibles y objetos de adicción. Esto es resultado de la reacción de Maillard, o glicación, que se produce por unión no enzimática del grupo carbonilo, de azú...
Abstract Introduction: Chronic kidney disease (CKD) is associated with high morbidity and mortality rates, main causes related with cardiovascular disease (CVD) and bone mineral disorder (CKD-BMD). Uremic toxins, as advanced glycation end products (AGEs), are non-traditional cardiovascular risk factor a...
ABSTRACT Objectives Advanced glycation end products (AGEs) are involved in the pathogenesis and complications of diabetes mellitus (DM). Gestational DM (GDM) is characterized by increased glycemia and oxidative stress, which are factors associated with high serum AGE concentrations. The aim of this stu...
Análisis de Varianza,
Antropometría,
Glucemia/análisis,
Estudios de Casos y Controles,
Creatinina/sangre,
Diabetes Gestacional/sangre,
Diabetes Gestacional/diagnóstico,
Fluorometría/métodos,
Edad Gestacional,
Productos Finales de Glicación Avanzada/sangre,
Tamizaje Masivo/métodos,
Valores de Referencia,
Reproducibilidad de los Resultados,
Sensibilidad y Especificidad,
Estadísticas no Paramétricas
Navarro, Maria Eugênia Lopes;
Santos, Klinsmann Carolo dos;
Nascimento, André Ferreira do;
Francisqueti, Fabiane Valentini;
Minatel, Igor Otávio;
Pierine, Damiana Tortolero;
Luvizotto, Renata Azevedo de Melo;
Ferreira, Ana Lúcia A;
Campos, Dijon Henrique Salomé de;
Corrêa, Camila Renata.
Resumo Introdução: A obesidade é uma doença em que a inflamação está inteiramente envolvida e pode causar insuficiência renal. Objetivo: Avaliar a influência da exposição a curto prazo de uma dieta de cafeteria sobre a inflamação no tecido renal e a formação de produtos de glicação ava...
