Behavioral effects of Bj-PRO-7a, a proline-rich oligopeptide from Bothrops jararaca venom
Braz. j. med. biol. res; 52 (11), 2019
The heptapeptide Bj-PRO-7a, isolated and identified from Bothrops jararaca (Bj) venom, produces antihypertensive and other cardiovascular effects that are independent on angiotensin converting enzyme inhibition, possibly relying on cholinergic muscarinic receptors subtype 1 (M1R). However, whether Bj-PRO...
Ansiedad, Conducta Animal/efectos de los fármacos, Conducta Animal/fisiología, Venenos de Crotálidos/química, Depresión, Conducta Exploratoria/efectos de los fármacos, Oligopéptidos/aislamiento & purificación, Oligopéptidos/farmacología, Prolina/aislamiento & purificación, Prolina/farmacología, Ratas Wistar