Application of a pharmacokinetics-pharmacodynamics approach to the free propofol plasma levels during coronary artery bypass grafting surgery with hypothermic cardiopulmonary bypass
Clinics; 73 (), 2018
OBJECTIVES: The objective of this study was to apply a pharmacokinetics-pharmacodynamics approach to investigate the free propofol plasma levels in patients undergoing coronary artery bypass grafting under hypothermic conditions compared with the off-pump procedure. METHODS: Nineteen patients scheduled ...
Anestésicos Intravenosos/sangre, Anestésicos Intravenosos/farmacocinética, Puente Cardiopulmonar/métodos, Monitores de Conciencia, Puente de Arteria Coronaria/métodos, Puente de Arteria Coronaria Off-Pump/métodos, Hipnosis Anestésica/normas, Hipotermia Inducida, Tempo Operativo, Propofol/sangre, Propofol/farmacocinética