Results: 2

AXIN2-associated adenomatous colorectal polyposis

Martins, Bruno Augusto Alves; Falluh Filho, Reinaldo; Almeida, Romulo Medeiros de; Sandoval, Renata Lazari.

J. coloproctol. (Rio J., Impr.); 41 (4), 2021

Abstract: Introduction Most cases of colorectal cancer (CRC) occur sporadically; however, ~3% to 6% of all CRCs are related to inherited syndromes, such as Lynch syndrome and familial adenomatous polyposis (FAP). The adenomatous polyposis coli (APC) andmutY DNA glycosylase (MUTYH) germline mutations are...

Poliposis Adenomatosa del Colon/diagnóstico, Mutación, Proteína Axina/genética

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Association of single nucleotide polymorphisms in AXIN2, BMP4, and IRF6 with Non-Syndromic Cleft Lip with or without Cleft Palate in a sample of the southeast Iranian population

Rafighdoost, Houshang; Hashemi, Mohammad; Danesh, Hiva; Bizhani, Fatemeh; Bahari, Gholamreza; Taheri, Mohsen.

J. appl. oral sci; 25 (6), 2017

Abstract Non-syndromic cleft lip with or without palate (NSCL/P) is a common congenital malformation worldwide, with complex etiology. It has been proposed that interaction of genes and environmental factors play a role in the predisposition to this disease. Objectives: The aim of this study was to exam...

Proteína Axina/genética, Proteína Morfogenética Ósea 4/genética, Estudios de Casos y Controles, Labio Leporino/genética, Fisura del Paladar/genética, Frecuencia de los Genes, Predisposición Genética a la Enfermedad, Genotipo, Factores Reguladores del Interferón/genética, Irán, Polimorfismo de Longitud del Fragmento de Restricción, Polimorfismo de Nucleótido Simple

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