Results: 3

Effect of lncRNA HULC knockdown on rat secreting pituitary adenoma GH3 cells

Braz. j. med. biol. res; 52 (4), 2019
Pituitary adenoma is one of the most common tumors in the neuroendocrine system. This study investigated the effects of long non-coding RNAs (lncRNAs) highly up-regulated in liver cancer (HULC) on rat secreting pituitary adenoma GH3 cell viability, migration, invasion, apoptosis, and hormone secretion, a...

Relevant coexpression of STMN1, MELK and FOXM1 in glioblastoma and review of the impact of STMN1 in cancer biology

OBJECTIVE: To analyze the associated expression of STMN1, MELK and FOXM1 in search of alternative drugable target in glioblastoma (GBM) and to review relevant functional roles of STMN1 in cancer biology. METHOD: STMN1, MELK and FOXM1 expressions were studied by quantitative PCR and their coexpressions w...

Avaliação de survivina e XIAP e dos fatores de transcrição foxo3a e foxM1 como potenciais biomarcadores de quimiorresistência no câncer de mama

O câncer de mama é a neoplasia que apresenta maior mortalidade entre as mulheres ao redor do mundo, apesar dos avanços na descoberta de novas modalidades terapêuticas e marcadores prognósticos. A resistência ao tratamento quimioterápico é uma das principais causas de falha terapêutica, apontando...