Results: 3

Atractylenolide III alleviates sepsis-mediated lung injury via inhibition of FoxO1 and VNN1 protein

Acta cir. bras; 36 (8), 2021
ABSTRACT Purpose: To evaluate the influence of atractylenolide (Atr) III on sepsis-induced lung damage. Methods: We constructed a mouse sepsis model through cecal ligation and puncture. These mice were allocated to the normal, sepsis, sepsis + Atr III-L (2 mg/kg), as well as Atr III-H (8 mg/kg) group. ...

Gramicidin inhibits human gastric cancer cell proliferation, cell cycle and induced apoptosis

Biol. Res; 52 (), 2019
BACKGROUND: Gastric cancer is a common malignant tumor with high morbidity and mortality worldwide, which seriously affects human health. Gramicidin is a short peptide antibiotic which could be used for treating infection induced by bacteria or fungi. However, the anti-cancer effect of gramicidin on gast...

Alterações Citogenético-Moleculares no Gene FOXO1 em uma Criança com Rabdomiossarcoma Alveolar: Relato de Caso

Rev. bras. cancerol; 64 (3), 2018
Introdução: o rabdomiossarcoma (rMs) é o tumor de tecidos moles mais comum da infância. Pode ser classificado em dois subtipos principais: o rabdomiossarcoma alveolar (rMsa) e o embrionário (rMse). no rMsa, o prognóstico é desfavorável quando comparado ao rMse, necessitando de tratamento intensif...