Results: 2

Comparative proteomic analysis of the nucleus accumbens during extinction and reinstatement of morphine dependence

Feng, K; Qiu, H; Gao, Y; Fu, Y; Du, L; Qiu, T; Meng, H; Luo, Q.

West Indian med. j; 62 (3), 2013

BACKGROUND: The aim of this study was to detect differentially expressed proteins in the nucleus accumbens between the states of extinction and reinstatement of morphine addiction. Numerous studies on the neurobiological mechanisms concerning drug craving and relapse have been reported to date, but data ...

Extinción Psicológica/fisiología, Proteínas de Unión a Ácidos Grasos/metabolismo, Proteínas HSP90 de Choque Térmico/metabolismo, Dependencia de Morfina/metabolismo, Núcleo Accumbens/metabolismo, Proteína Fosfatasa 2/metabolismo, Proteoma, Ratas Sprague-Dawley, Refuerzo en Psicología

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Effects of intrahippocampal administration of the phosphatase inhibitor okadaic acid: dual effects on memory formation

Vianna, Monica RM; Coutinho, Adriana; Izquierdo, Luciana; Izquierdo, Ivan.

Dement. neuropsychol; 4 (1), 2010

Protein phosphorylation mediated by serine-threonine kinases in the hippocampus is crucial to the synaptic modifications believed to underlie memory formation. The role of phosphatases has been the focus of comparatively little study. Objectives: Here we evaluate the contribution of the serine-threonine ...

Hipocampo, Proteína Fosfatasa 1, Proteína Fosfatasa 2, Ácido Ocadaico, Memoria a Corto Plazo, Memoria a Largo Plazo

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