LncRNA LINC00483 promotes gastric cancer development through regulating MAPK1 expression by sponging miR-490-3p
Biol. Res; 53 (), 2020
BACKGROUND: Previous studies have shown that long noncoding RNA (IncRNA) LINC00483 was aberrantly expressed in human cancers, including gastric cancer. However, the regulatory mechanism of this IncRNA in gastric cancer remains largely unknown. The present study aimed to investigate the effect of LINC0048...
MicroARNs/metabolismo, Proteína Quinasa 1 Activada por Mitógenos/metabolismo, ARN Largo no Codificante/metabolismo, Neoplasias Gástricas/metabolismo, Carcinogénesis/metabolismo, Línea Celular Tumoral/metabolismo, Células Epiteliales/metabolismo, Luciferasas/metabolismo, MicroARNs/genética, ARN Largo no Codificante/genética, Neoplasias Gástricas/genética, Apoptosis, Movimiento Celular, Supervivencia Celular, Regulación Neoplásica de la Expresión Génica, Ratones Endogámicos BALB C, Ensayos Antitumor por Modelo de Xenoinjerto