Ca2+/Calmodulin-dependent kinase II delta B is essential for cardiomyocyte hypertrophy and complement gene expression after LPS and HSP60 stimulation in vitro
Braz. j. med. biol. res; 52 (7), 2019
Inflammation plays an important role in the development of cardiovascular diseases (CVDs), suggesting that the immune system is a target of therapeutic interventions used for treating CVDs. This study evaluated mechanisms underlying inflammatory response and cardiomyocyte hypertrophy associated with bact...
Proteína Quinasa Tipo 2 Dependiente de Calcio Calmodulina/metabolismo, Chaperonina 60/farmacología, Expresión Génica, Inflamación/metabolismo, Lipopolisacáridos/farmacología, Miocitos Cardíacos/efectos de los fármacos, Miocitos Cardíacos/metabolismo, Miocitos Cardíacos/patología, FN-kappa B/metabolismo, ARN Interferente Pequeño, Ratas Wistar, Transducción de Señal/fisiología, Receptores Toll-Like/metabolismo