LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Subcellular localisation of FLAG tagged enzymes of the dynamic protein S-palmitoylation cycle of Trypanosoma cruzi epimastigotes

Batista, Cassiano Martin; Saad, Felipe; Ceccoti, Stephane Pini Costa; Eger, Iriane; Soares, Maurilio José.

Mem. Inst. Oswaldo Cruz; 113 (8), 2018

Dynamic S-palmitoylation of proteins is the addition of palmitic acid by zDHHC palmitoyl transferases (PATs) and depalmitoylation by palmitoyl protein thioesterases (PPTs). A putative PAT (TcPAT1) has been previously identified in Trypanosoma cruzi, the etiological agent of Chagas disease. Here we analys...

Regulación de la Expresión Génica, Lipoilación/genética, Palmitatos/metabolismo, Proteína S/genética, Proteína S/metabolismo, Proteínas Protozoarias/genética, Proteínas Protozoarias/metabolismo, Trypanosoma cruzi/enzimología, Trypanosoma cruzi/genética, Trypanosoma cruzi/metabolismo

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