Benzyl isothiocyanate inhibits invasion and induces apoptosis via reducing S100A4 expression and increases PUMA expression in oral squamous cell carcinoma cells
Braz. j. med. biol. res; 52 (4), 2019
Benzyl isothiocyanate (BITC) has been shown to inhibit invasion and induce apoptosis of various types of cancer. However, its role on human oral squamous cell carcinoma (OSCC) cells is still not well elucidated. In the present study, we investigated the effect of BITC on apoptosis and invasion of SCC9 ce...
Apoptosis/efectos de los fármacos, Carcinoma de Células Escamosas/patología, Línea Celular Tumoral, Movimiento Celular/efectos de los fármacos, Proliferación Celular/efectos de los fármacos, Supervivencia Celular/efectos de los fármacos, Inmunohistoquímica, Isotiocianatos/farmacología, Ratones Desnudos, Proteína de Unión al Calcio S100A4/efectos de los fármacos, Proteína de Unión al Calcio S100A4/metabolismo