Improving adenoviral vectors and strategies for prostate cancer gene therapy
Clinics; 73 (supl.1), 2018
Gene therapy has been evaluated for the treatment of prostate cancer and includes the application of adenoviral vectors encoding a suicide gene or oncolytic adenoviruses that may be armed with a functional transgene. In parallel, versions of adenoviral vector expressing the p53 gene (Ad-p53) have been te...
Adenoviridae/genética, Carcinoma de Pulmón de Células no Pequeñas/genética, Genes Transgénicos Suicidas, Terapia Genética/métodos, Vectores Genéticos/uso terapéutico, Neoplasias Pulmonares/genética, Proteínas de Neoplasias/genética, Antígeno Prostático Específico/genética, Neoplasias de la Próstata/genética, Neoplasias de la Próstata/inmunología, Neoplasias de la Próstata/terapia, Proteína p53 Supresora de Tumor/biosíntesis