Results: 6

Inmunohistoquímica de p16 y p53 en cáncer de vulva

Immunohistochemistry of p16 and p53 in vulvar cancer

Falcón, Maria Florencia; Paradeda, María Eugenia; García Kamermann, Florencia; Maldonado, Verónica; Díaz, Lili; Cardinal, Lucía.

Medicina (B.Aires); 80 (2), 2020

El carcinoma escamoso vulvar puede desarrollarse de manera asociada o independiente a la infección por HPV. La relación entre la patogénesis, la clasificación, el perfil inmunohistoquímico, y el pronóstico ha sido estudiada con algunas discrepancias. El objetivo del trabajo fue observar la concorda...

Biomarcadores de Tumor, Carcinogénesis, Carcinoma de Células Escamosas/diagnóstico, Carcinoma de Células Escamosas/metabolismo, Inmunohistoquímica, Papillomaviridae, Infecciones por Papillomavirus, Proteína p53 Supresora de Tumor/metabolismo, Neoplasias de la Vulva/diagnóstico, Neoplasias de la Vulva/metabolismo, Verrugas

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Icariin reduces human colon carcinoma cell growth and metastasis by enhancing p53 activities

Tian, Meili; Yang, Shuang; Yan, Xinpeng.

Braz. j. med. biol. res; 51 (10), 2018

Icariin has been reported to possess high anticancer activity. Colon carcinoma is one of the leading causes of cancer-related mortality worldwide. Here, the anticancer activity of icariin against HCT116 colon carcinoma cells and the possible underlying mechanism were studied. The trypan blue staining ass...

Antineoplásicos Fitogénicos/farmacología, Apoptosis/efectos de los fármacos, Western Blotting, Movimiento Celular/efectos de los fármacos, Proliferación Celular/efectos de los fármacos, Neoplasias del Colon/metabolismo, Neoplasias del Colon/patología, Flavonoides/farmacología, Células HCT116, ARN Interferente Pequeño, Reacción en Cadena en Tiempo Real de la Polimerasa, Proteína p53 Supresora de Tumor/efectos de los fármacos, Proteína p53 Supresora de Tumor/metabolismo

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Caracterização dos fenótipos de mucina podem prever a recorrência do câncer gástrico precoce após a mucosectomia endoscópica

Hondo, Fabio Yuji; Kishi, Humberto; Safatle-Ribeiro, Adriana Vaz; Pessorrusso, Fernanda Cristina Simões; Ribeiro Jr, Ulysses; Maluf-Filho, Fauze.

Arq. gastroenterol; 54 (4), 2017

ABSTRACT BACKGROUND: Endoscopic mucosal resection is still considered an accepted treatment for early gastric cancer for selected cases. Histopathologic criteria for curative endoscopic resection are intramucosal well-differentiated adenocarcinoma, lateral and deep margins free of tumor, no histological...

Adenocarcinoma/clasificación, Adenocarcinoma/metabolismo, Adenocarcinoma/cirugía, Biomarcadores de Tumor/metabolismo, Resección Endoscópica de la Mucosa, Mucosa Gástrica/patología, Mucosa Gástrica/cirugía, Antígeno Ki-67/metabolismo, Persona de Mediana Edad, Mucinas, Recurrencia Local de Neoplasia/metabolismo, Fenotipo, Neoplasias Gástricas/clasificación, Neoplasias Gástricas/metabolismo, Neoplasias Gástricas/cirugía, Proteína p53 Supresora de Tumor/metabolismo

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Post-immunization immunohistochemical expression of Caspase 3 and p53 apoptotic markers in experimental hydatidosis

El-Aal, Amany Ahmed Abd; El-Gebaly, Naglaa Saad Mahmoud; Al-Antably, Abeer Said; Hassan, Marwa Adel; El-Dardiry, Marwa Ahmed.

Rev. bras. parasitol. vet; 25 (3), 2016

Abstract The aim of this study was to investigate post-immunization apoptotic changes in experimental hydatidosis, using Caspase 3 and p53 immunohistochemical markers. Two groups of rabbits were immunized with a crude antigen (group 1) or a partially purified antigen (group 2) and were compared to an inf...

Apoptosis, Caspasa 3/metabolismo, Equinococosis/metabolismo, Equinococosis/prevención & control, Equinococosis/veterinaria, Inmunización/veterinaria, Proteína p53 Supresora de Tumor/metabolismo, Vacunación

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Schirrous invasive ductal carcinoma of the breast overexpress p53 oncoprotein

Ferrini, Flávia Silva; Rossi, Marcos Antonio; Mouräo Neto, Mário; Soares, Fernando Augusto.

Säo Paulo med. j; 119 (1), 2001

CONTEXT: Breast cancer is the most important neoplasm in adult women, and its worldwide incidence is growing. The tumoral stroma is very important for modulating the growth and invasion of the tumor itself. The relationship between these two components is not completely understood. Schirrous carcinoma is...

Neoplasias de la Mama/patología, Proteína p53 Supresora de Tumor/metabolismo, Receptor ErbB-2/metabolismo, Carcinoma Ductal de Mama/patología, Carcinoma Ductal de Mama/metabolismo, Neoplasias de la Mama/metabolismo, Biomarcadores de Tumor/metabolismo, Proteínas de Neoplasias/metabolismo, Estudios Retrospectivos

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P53 regulation and function in normal cells and tumors

Liu, Y; Kulesz-Martin, M.

Medicina (B.Aires); 60 Suppl 2 (), 2000

Mechanisms to protect organisms from the consequences of DNA damage include the tumor suppressor p53 pathway. p53 protein binds specifically to a DNA consensus sequence to induce growth inhibitory genes or nonspecifically to damaged sites leading to DNA repair or apoptosis. While p53 protein is susceptib...

Apoptosis, Carcinoma de Células Escamosas/metabolismo, Reparación del ADN, Proteínas de Unión al ADN/metabolismo, Regulación Neoplásica de la Expresión Génica, Proteínas de Neoplasias/metabolismo, Proteínas de Neoplasias/fisiología, Proteína p53 Supresora de Tumor/metabolismo, Proteína p53 Supresora de Tumor/fisiología