Telomere Attrition and p53 Response 1 (TAPR1): a new player in cancer biology?
Clinics; 76 (), 2021
Results: 7
Tracing the origin of the NS1 A188V substitution responsible for recent enhancement of Zika virus Asian genotype infectivity
Mem. Inst. Oswaldo Cruz; 112 (11), 2017
A recent study showed that infectivity of Zika virus (ZIKV) Asian genotype was enhanced by an alanine-to-valine amino acid substitution at residue 188 of the NS1 protein, but the precise time and location of origin of this mutation were not formally estimated. Here, we applied a Bayesian coalescent-based...
Characterization of OAZ1 and its potential functions in goose follicular development
Electron. j. biotechnol; 26 (), 2017
Background: Ornithine decarboxylase antizyme 1 (OAZ1) is an important regulator of polyamine synthesis and uptake. Our previous studies indicated that high OAZ1 expression in the ovaries of laying geese is responsible for poor egg production. In the present study, the molecular characterization of goose ...
Proteínas/metabolismo, Proteínas/genética, Gansos/metabolismo, Análisis de Secuencia, Clonación Molecular, Folículo Ovárico/metabolismo, Folículo Ovárico/crecimiento & desarrollo, Poliaminas/metabolismo, ADN Complementario, ARN Mensajero, Reacción en Cadena en Tiempo Real de la Polimerasa, Ornitina Descarboxilasa/metabolismo
FAMLF is a target of miR-181b in Burkitt lymphoma
Braz. j. med. biol. res; 50 (6), 2017
Burkitt lymphoma (BL) is a highly malignant non-Hodgkin's lymphoma that is closely related to the abnormal expression of genes. Familial acute myelogenous leukemia related factor (FAMLF; GenBank accession No. EF413001.1) is a novel gene that was cloned by our research group, and miR-181b is located in th...
Apoptosis/genética, Linfoma de Burkitt/genética, Linfoma de Burkitt/metabolismo, Línea Celular Tumoral, Proliferación Celular/genética, Supervivencia Celular/genética, Regulación hacia Abajo/genética, Regulación Neoplásica de la Expresión Génica, MicroARNs/genética, MicroARNs/metabolismo, Proteínas/genética, Proteínas/metabolismo
Total protein composition of young and adult Biomphalaria alexandrina snails with different compatibilities to Schistosoma mansoni infection
Rev. biol. trop; 64 (4), 2016
Abstract:Schistosomiasis remains a disease of major global public health concern since it is a chronic and debilitating illness. The widely distributed Schistosoma mansoni that causes intestinal schistosomiasis represents a great threat. Its world-wide distribution is permitted by the broad geographic ra...
Factores de Edad, Biomarcadores/análisis, Biomphalaria/química, Biomphalaria/genética, Biomphalaria/parasitología, Electroforesis en Gel de Poliacrilamida, Interacciones Huésped-Parásitos, Peso Molecular, Proteínas/análisis, Proteínas/genética, Valores de Referencia, Esquistosomiasis mansoni/parasitología
Liver proteome of mice with different genetic susceptibilities to the effects of fluoride
J. appl. oral sci; 24 (3), 2016
ABSTRACT A/J and 129P3/J mice strains have been widely studied over the last few years because they respond quite differently to fluoride (F) exposure. 129P3/J mice are remarkably resistant to the development of dental fluorosis, despite excreting less F in urine and having higher circulating F levels. T...
Fluoruros/análisis, Fluoruros/metabolismo, Fluoruros/toxicidad, Fluorosis Dental/genética, Expresión Génica, Predisposición Genética a la Enfermedad, Hígado/efectos de los fármacos, Hígado/metabolismo, Espectrometría de Masas/métodos, Ratones de la Cepa 129, Ratones Endogámicos A, Estrés Oxidativo/efectos de los fármacos, Dominios y Motivos de Interacción de Proteínas, Proteínas/análisis, Proteínas/efectos de los fármacos, Proteínas/genética, Proteoma/efectos de los fármacos, Proteómica/métodos, Valores de Referencia, Factores de Tiempo
Detección de proteínas transgénicas en harinas de maíz comercializadas en Bogotá, Colombia
Rev. salud pública; 18 (3), 2016
Objetivo Detectar la presencia o ausencia de proteínas transgénicas derivadas de cultivos genéticamente modificados (GM) en harina de maíz comercializadas en Bogotá D.C., Colombia. Métodos Se evaluaron 11 protocolos de extracción de proteína total en 17 harinas pre-cocidas, dos no cocidas y tres ...