Assessing and screening for T-cell epitopes from Mycobacterium tuberculosis RD2 proteins for the diagnosis of active tuberculosis
Braz. j. infect. dis; 22 (6), 2018
ABSTRACT The Region of D eletion 2 (RD2) of Mycobacterium tuberculosis encodes reserved antigens that contribute to bacterial virulence. Among these antigens, Rv1983, Rv1986, Rv1987, and Rv1989c have been shown to be immunodominant in infected cattle; however, their diagnostic utility has not been evalua...
Antígenos Bacterianos/sangre, Antígenos Bacterianos/inmunología, Proteínas Bacterianas/sangre, Proteínas Bacterianas/inmunología, Estudios de Casos y Controles, Epítopos de Linfocito T/sangre, Epítopos de Linfocito T/inmunología, Mycobacterium tuberculosis/inmunología, Estudios Retrospectivos, Sensibilidad y Especificidad, Tuberculosis/diagnóstico, Tuberculosis/inmunología, Tuberculosis Pulmonar/diagnóstico, Tuberculosis Pulmonar/inmunología