LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

lncRNA KCNQ1OT1 reverses the effect of sevoflurane on hepatocellular carcinoma progression via regulating the miR-29a-3p/CBX3 axis

Zhou, Weifu; Li, Hui; Shang, Shuo; Liu, Feng.

Braz. j. med. biol. res; 54 (7), 2021

Sevoflurane (SEVO) is widely applied as an anesthetic, which exerts antitumor capacity in various cancers, including hepatocellular carcinoma (HCC). Previous studies indicated that long non-coding RNA KCNQ1 opposite strand/antisense transcript 1 (KCNQ1OT1) was upregulated, while microRNA-29a-3p (miR-29a-...

Carcinoma Hepatocelular/tratamiento farmacológico, Carcinoma Hepatocelular/genética, Proteínas Cromosómicas no Histona, Neoplasias Hepáticas/tratamiento farmacológico, Neoplasias Hepáticas/genética, MicroARNs/genética, Canales de Potasio con Entrada de Voltaje, ARN Largo no Codificante/genética, Sevoflurano/farmacología

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Actin filaments mediated root growth inhibition by changing their distribution under UV-B and hydrogen peroxide exposure in Arabidopsis

BACKGROUND: UV-B signaling in plants is mediated by UVR8, which interacts with transcriptional factors to induce root morphogenesis. However, research on the downstream molecules of UVR8 signaling in roots is still scarce. As a wide range of functional cytoskeletons, how actin filaments respond to UV-B-i...