Speckle type POZ adaptor protein (SPOP) and its role in cancer
Rev. colomb. cancerol; 25 (3), 2021
Abstract Proteasomal degradation is an essential regulatory mechanism for cellular homeostasis maintenance. The speckle-type POZ adaptor protein (SPOP) is part of the ubiquitin ligase E3 cullin-3 RING-box1 complex, responsible for the ubiquitination and proteasomal degradation of biomolecules involved in...