LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Prognostic significance of the mad1l1 1673 g:a polymorphism in ovarian adenocarcinomas

Bandala-Jacques, Antonio; Hernández-Cruz, Irwin A.; Castro-Hernández, Clementina; Díaz-Chávez, José; Arriaga-Canon, Cristian; Barquet-Muñoz, Salim A.; Prada-Ortega, Diddier G.; Cantú-de León, David; Herrera, Luis A..

Rev. invest. clín; 72 (6), 2020

Abstract Background: Ovarian cancer is the most lethal gynecologic cancer. Although most patients respond adequately to the first-line therapy, up to 85% experience a recurrence of disease, which carries a poor prognosis. Mitotic arrest deficiency 1 is a protein that helps in the assembly of the mitotic...

Adenocarcinoma/genética, Adenocarcinoma/mortalidad, Proteínas de Ciclo Celular/genética, Neoplasias Ováricas/genética, Neoplasias Ováricas/mortalidad, Polimorfismo de Nucleótido Simple, Pronóstico, Estudios Retrospectivos, Tasa de Supervivencia

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REC8 suppresses tumor angiogenesis by inhibition of NF-κB-mediated vascular endothelial growth factor expression in gastric cancer cells

Liu, Miao; Xu, Wanfu; Su, Mingmin; Fan, Pingsheng.

Biol. Res; 53 (), 2020

BACKGROUND: Tumor angiogenesis is an essential event for tumor growth and metastasis. It has been showed that REC8, a component of the meiotic cohesion complex, played a vital role in Epithelial-Mesenchymal Transition (EMT) in gastric cancer. However, the role of REC8 in gastric cancer angiogenesis remai...

Proteínas de Ciclo Celular/genética, FN-kappa B/genética, Neovascularización Patológica/genética, Neoplasias Gástricas/patología, Factor A de Crecimiento Endotelial Vascular/genética, Neoplasias Gástricas/irrigación sanguínea, Línea Celular Tumoral, Células Endoteliales de la Vena Umbilical Humana, Microambiente Tumoral

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The apoptotic, angiogenic and cell proliferation genes CD63, S100A6 e GNB2L1 are altered in patients with endometriosis

Gomes, Valéria Aguiar; Bonocher, Camila de Moraes; Rosa-e-Silva, Júlio César; Paz, Cláudia Cristina Paro de; Ferriani, Rui Alberto; Meola, Juliana.

Rev. bras. ginecol. obstet; 40 (10), 2018

Abstract Objective The aim of the present study was to analyze the expression of the CD63, S100A6, and GNB2L1genes, which participate in mechanisms related to the complex pathophysiology of endometriosis. Methods A case-control study was conducted with 40 women who were diagnosed with endometriosis, ...

Apoptosis/genética, Estudios de Casos y Controles, Proteínas de Ciclo Celular/genética, Proliferación Celular/genética, Endometriosis/genética, Endometriosis/patología, Expresión Génica, Proteínas de Neoplasias/genética, Neovascularización Patológica/genética, Receptores de Cinasa C Activada/genética, Proteína A6 de Unión a Calcio de la Familia S100/genética, Tetraspanina 30/genética

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