SUMMARY: The geese's tongue filiform papillae are particularly long, and exhibit the same morphology of a tooth, evoking the lingual teeth of several fishes. In adult animals, they contain numerous mechanical Herbst's corpuscles but no taste buds. In the embryo, they appear since stage 38 and acquire the...
SUMMARY: Recent studies have shown that homeobox proteins play an important role in the formation and development of tissues and organs in the embryonic period. In our study, the distribution of Dlx-5 and TLX proteins, which are members of the homeobox family, in the testis, epididymis and ductus deferen...
Abstract Introduction: Non-syndromic cleft lip with or without cleft palate is a common worldwide birth defect due to a combination of environmental and genetic factors. Genome-wide association studies reported the rs7078160 of Vax1 is closely related to non-syndromic cleft lip with or without cleft pal...
Abstract The Inhibitor of Growth (ING) gene family is a group of tumor suppressor genes that play important roles in cell cycle control, senescence, DNA repair, cell proliferation, and apoptosis. However, inactivation and downregulation of these proteins have been related in some neoplasms. The present s...
Tobacco can induce reactive oxygen species (ROS) production extensively in cells, which is a major risk factor for oral leukoplakia (OLK) development. Peroxiredoxin 1 (Prx1) is a key antioxidant protein, upregulated in a variety of malignant tumors. We previously found that nicotine, the main ingredient ...
ABSTRACT The first description of patients with combined pituitary hormone deficiencies (CPHD) caused by PROP1 mutations was made 20 years ago. Here we updated the clinical and genetic characteristics of patients with PROP1 mutations and summarized the phenotypes of 14 patients with 7 different pathogeni...
Objective To describe the frequency of mutations in DNA-repair genes in a southwestern Colombian population.
Methods We have designed an observational study, including 162 people from all ages from southwest Colombia. We have extracted and collected their DNA in filters. We have immersed the DNA in a...
Colombia,
ADN,
Articulación Temporomandibular,
Ataxia Telangiectasia,
Molécula de Adhesión Celular Epitelial,
Genes,
Neoplasias,
Polimorfismo de Nucleótido Simple,
Programas Informáticos,
Proteínas MutS,
Proteínas de Homeodominio,
Quinasa de Punto de Control 2,
Reparación de la Incompatibilidad de ADN,
Reparación del ADN
Summary Introduction: Prostate cancer is the second type of cancer diagnosed and the fifth cause of death in men worldwide. Early diagnosis helps to control disease progression. Currently, prostate specific antigen is the standard biomarker, as it has a broad scope of identification and, thus, new and m...
BACKGROUND: MiR-320 is downregulated in multiple cancers, including glioma and acts as tumor suppressor through inhibiting tumor cells proliferation and inducing apoptosis. PBX3 (Pre-B cell leukemia homeobox 3), a putative target gene of miR-320, has been reported to be upregulated in various tumors and ...
Neoplasias Encefálicas/metabolismo,
Glioma/metabolismo,
Proteínas de Homeodominio/metabolismo,
MicroARNs/metabolismo,
Proteínas Proto-Oncogénicas/metabolismo,
Neoplasias Encefálicas/patología,
Diferenciación Celular/efectos de los fármacos,
Proliferación Celular/efectos de los fármacos,
Glioma/patología,
Línea Celular Tumoral,
Regulación hacia Abajo,
Regulación Neoplásica de la Expresión Génica,
Regulación hacia Arriba
BACKGROUND: Pure mucinous adenocarcinoma of the breast is a rare entity characterized by the production of variable amounts of mucin comprising 1% to 6% of breast carcinomas. Some mucinous adenocarcinomas have shown expression of intestinal differentiation markers such as MUC-2. This study examines the e...
Adenocarcinoma Mucinoso/química,
Biomarcadores de Tumor/análisis,
Neoplasias de la Mama/química,
Proteínas de Homeodominio/análisis,
Mucosa Intestinal/química,
Mucina 2/análisis,
Transactivadores,
beta Catenina/análisis,
Adenocarcinoma Mucinoso/patología,
Antígenos de Diferenciación/análisis,
Neoplasias de la Mama/patología,
Factor de Transcripción CDX2,
Inmunohistoquímica,
Estudios Retrospectivos
